Pharmacologic HIF stabilization activates costimulatory receptor expression to increase antitumor efficacy of adoptive T cell therapy
Adoptive cell transfer (ACT) is a therapeutic strategy to augment antitumor immunity. Here,
we report that ex vivo treatment of mouse CD8+ T cells with dimethyloxalylglycine (DMOG) …
we report that ex vivo treatment of mouse CD8+ T cells with dimethyloxalylglycine (DMOG) …
Nano-Pulse Treatment Overcomes the Immunosuppressive Tumor Microenvironment to Elicit In Situ Vaccination Protection against Breast Cancer
A Nanajian, M Scott, NI Burcus, BL Ruedlinger… - Vaccines, 2024 - mdpi.com
We previously reported that nano-pulse treatment (NPT), a pulsed power technology,
resulted in 4T1-luc mammary tumor elimination and a strong in situ vaccination, thereby …
resulted in 4T1-luc mammary tumor elimination and a strong in situ vaccination, thereby …