Predictors of primary response to biologic treatment [anti-TNF, vedolizumab, and ustekinumab] in patients with inflammatory bowel disease: from basic science to …

JP Gisbert, M Chaparro - Journal of Crohn's and Colitis, 2020 - academic.oup.com
Background Inflammatory bowel diseases [IBD]―ulcerative colitis and Crohn's disease―are
commonly treated with biologic drugs. However, only approximately two-thirds of patients …

Management strategies to improve outcomes of patients with inflammatory bowel diseases

JF Colombel, N Narula, L Peyrin-Biroulet - Gastroenterology, 2017 - Elsevier
Strategies for management of inflammatory bowel diseases are shifting from simple control
of symptoms toward full control of these diseases (clinical and endoscopic remission), with …

Remicade® (infliximab): 20 years of contributions to science and medicine

R Melsheimer, A Geldhof, I Apaolaza… - Biologics: Targets and …, 2019 - Taylor & Francis
Abstract On August 24, 1998, Remicade®(infliximab), the first tumor necrosis factor-α (TNF)
inhibitor, received its initial marketing approval from the US Food and Drug Administration …

[HTML][HTML] Screening and early diagnosis of osteoporosis through X-ray and ultrasound based techniques

P Pisani, MD Renna, F Conversano… - World journal of …, 2013 - ncbi.nlm.nih.gov
Effective prevention and management of osteoporosis would require suitable methods for
population screenings and early diagnosis. Current clinically-available diagnostic methods …

[HTML][HTML] Biomarkers in inflammatory bowel diseases: current status and proteomics identification strategies

T Bennike, S Birkelund, A Stensballe… - World Journal of …, 2014 - ncbi.nlm.nih.gov
Unambiguous diagnosis of the two main forms of inflammatory bowel diseases (IBD):
Ulcerative colitis (UC) and Crohn's disease (CD), represents a challenge in the early stages …

Quantitative proteomic analysis reveals the deregulation of nicotinamide adenine dinucleotide metabolism and CD38 in inflammatory bowel disease

LG Ning, G Shan, Z Sun, F Zhang, C Xu… - BioMed research …, 2019 - Wiley Online Library
Inflammatory bowel disease (IBD) has become a major health challenge worldwide.
However, the precise etiological and pathophysiological factors involved in IBD remain …

Proteomic analysis of ascending colon biopsies from a paediatric inflammatory bowel disease inception cohort identifies protein biomarkers that differentiate Crohn's …

AE Starr, SA Deeke, Z Ning, CK Chiang, X Zhang… - Gut, 2017 - gut.bmj.com
Objective Accurate differentiation between Crohn's disease (CD) and UC is important to
ensure early and appropriate therapeutic intervention. We sought to identify proteins that …

Clinical usefulness of proteomics in inflammatory bowel disease: a comprehensive review

JP Gisbert, M Chaparro - Journal of Crohn's and Colitis, 2019 - academic.oup.com
The protein domain is probably the most ubiquitously affected in disease, response and
recovery, and therefore proteomics holds special promise for biomarker discovery in …

[HTML][HTML] A personalized approach to managing inflammatory bowel disease

MJ Kingsley, MT Abreu - Gastroenterology & hepatology, 2016 - ncbi.nlm.nih.gov
The management of inflammatory bowel disease (IBD) requires a personalized approach to
treat what is a heterogeneous group of patients with inherently variable disease courses. In …

[HTML][HTML] Alterations and potential applications of gut microbiota in biological therapy for inflammatory bowel diseases

D Pu, Z Zhang, B Feng - Frontiers in Pharmacology, 2022 - frontiersin.org
Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is a
chronic immune-mediated inflammatory disorder of the gastrointestinal tract that is closely …