Mitochondrial fatty acid β-oxidation (FAO) is the major pathway for the degradation of fatty
acids and is essential for maintaining energy homeostasis in the human body. Fatty acids …

Mammalian skeletal muscle comprises different fiber types, whose identity is first established
during embryonic development by intrinsic myogenic control mechanisms and is later …

In mammals, excess energy is stored primarily as triglycerides, which are mobilized when
energy demands arise. This review mainly focuses on the role of long chain fatty acids …

Skeletal muscle fitness and plasticity is an important determinant of human health and
disease. Mitochondria are essential for maintaining skeletal muscle energy homeostasis by …

Previous studies have suggested that insulin resistance develops secondary to diminished
fat oxidation and resultant accumulation of cytosolic lipid molecules that impair insulin …

Obesity and the related disorders of dyslipidemia and diabetes (components of syndrome X)
have become global health epidemics. Over the past decade, the elucidation of key …

Complex interplay between T helper (Th) cells and macrophages contributes to the
formation and progression of atherosclerotic plaques. While Th1 cytokines promote …

Energy metabolism is a basic and general process, by which the body acquires and uses
energy to maintain normal function, and taurine plays a vital role in energy metabolism …

The three peroxisome proliferator-activated receptors (PPARs) are ligand-activated
transcription factors of the nuclear hormone receptor superfamily. They share a high degree …

Endurance exercise training can promote an adaptive muscle fiber transformation and an
increase of mitochondrial biogenesis by triggering scripted changes in gene expression …