[HTML][HTML] Plant-derived compounds in treatment of leishmaniasis
A Oryan - Iranian journal of veterinary research, 2015 - ncbi.nlm.nih.gov
Leishmaniasis is a neglected public health problem caused by the protozoan species
belonging to the genus Leishmania affecting mostly the poor populations of developing …
belonging to the genus Leishmania affecting mostly the poor populations of developing …
[HTML][HTML] Piper aduncum essential oil: a promising insecticide, acaricide and antiparasitic. A review
Several studies have assessed the potential of essential oils as substitutes for synthetic
pesticides, in order to counter insect resistance to commercial pesticides. Piper aduncum L …
pesticides, in order to counter insect resistance to commercial pesticides. Piper aduncum L …
Oxidative stress triggered by apigenin induces apoptosis in a comprehensive panel of human cervical cancer‐derived cell lines
RP Souza, PS Bonfim-Mendonca… - Oxidative medicine …, 2017 - Wiley Online Library
Recently, the cytotoxic effects of apigenin (4′, 5, 7‐trihydroxyflavone), particularly its
marked inhibition of cancer cell viability both in vitro and in vivo, have attracted the attention …
marked inhibition of cancer cell viability both in vitro and in vivo, have attracted the attention …
[HTML][HTML] Carajurin Induces Apoptosis in Leishmania amazonensis Promastigotes through Reactive Oxygen Species Production and Mitochondrial Dysfunction
JV Silva-Silva, CJ Moragas-Tellis, MSS Chagas… - Pharmaceuticals, 2022 - mdpi.com
Carajurin is the main constituent of Arrabidaea chica species with reported anti-Leishmania
activity. However, its mechanism of action has not been described. This study investigated …
activity. However, its mechanism of action has not been described. This study investigated …
[HTML][HTML] The potential of traditional knowledge to develop effective medicines for the treatment of leishmaniasis
LFD Passero, ES Brunelli, T Sauini… - Frontiers in …, 2021 - frontiersin.org
Leishmaniasis is a neglected tropical disease that affects people living in tropical and
subtropical areas of the world. There are few therapeutic options for treating this infectious …
subtropical areas of the world. There are few therapeutic options for treating this infectious …
[HTML][HTML] Cell death and ultrastructural alterations in Leishmania amazonensis caused by new compound 4-Nitrobenzaldehyde thiosemicarbazone derived from S …
EA Britta, DB Scariot, H Falzirolli, T Ueda-Nakamura… - BMC microbiology, 2014 - Springer
Background The treatment of leishmaniasis with pentavalent antimonials is problematic
because of their toxicity. Investigations of potentially active molecules are important to …
because of their toxicity. Investigations of potentially active molecules are important to …
Nerolidol, the main constituent of Piper aduncum essential oil, has anti-Leishmania braziliensis activity
LF Ceole, MDG Cardoso, MJ Soares - Parasitology, 2017 - cambridge.org
Leishmania (Viannia) braziliensis is a protozoan that causes mucocutaneous leishmaniasis,
which is an infectious disease that affects more than 12 million people worldwide. The …
which is an infectious disease that affects more than 12 million people worldwide. The …
[HTML][HTML] Linalool, a Piper aduncum essential oil component, has selective activity against Trypanosoma cruzi trypomastigote forms at 4°C
LH Villamizar, MG Cardoso, J Andrade… - Memórias do Instituto …, 2017 - SciELO Brasil
BACKGROUND Recent studies showed that essential oils from different pepper species
(Piper spp.) have promising leishmanicidal and trypanocidal activities. OBJECTIVES In …
(Piper spp.) have promising leishmanicidal and trypanocidal activities. OBJECTIVES In …
[HTML][HTML] Natural compounds based chemotherapeutic against Chagas disease and leishmaniasis: Mitochondrion as a strategic target
D Lazarin-Bidóia, FP Garcia… - Memórias do Instituto …, 2022 - SciELO Brasil
Over the past years, natural products have been explored in order to find biological active
substances to treat various diseases. Regarding their potential action against parasites such …
substances to treat various diseases. Regarding their potential action against parasites such …
[HTML][HTML] Potential of Piper spp. as a source of new compounds for the leishmaniases treatment
JF Peixoto, YJ Ramos, D de Lima Moreira… - Parasitology …, 2021 - Springer
Current treatment guidelines for leishmaniasis is based on chemotherapy with drugs that
show a set of limitations such as high cost, toxicity, difficult route of administration, and lack …
show a set of limitations such as high cost, toxicity, difficult route of administration, and lack …