Representational drift: Emerging theories for continual learning and experimental future directions

LN Driscoll, L Duncker, CD Harvey - Current Opinion in Neurobiology, 2022 - Elsevier
Recent work has revealed that the neural activity patterns correlated with sensation,
cognition, and action often are not stable and instead undergo large scale changes over …

Multiregion neuronal activity: the forest and the trees

TA Machado, IV Kauvar, K Deisseroth - Nature Reviews Neuroscience, 2022 - nature.com
The past decade has witnessed remarkable advances in the simultaneous measurement of
neuronal activity across many brain regions, enabling fundamentally new explorations of the …

Neuropixels 2.0: A miniaturized high-density probe for stable, long-term brain recordings

NA Steinmetz, C Aydin, A Lebedeva, M Okun… - Science, 2021 - science.org
INTRODUCTION Electrode arrays based on complementary metal-oxide semiconductor
silicon fabrication technology, such as Neuropixels probes, have enabled recordings of …

Organization of neural circuits underlying social behavior: a consideration of the medial amygdala

T Raam, W Hong - Current opinion in neurobiology, 2021 - Elsevier
The medial amygdala (MeA) is critical for the expression of a broad range of social
behaviors, and is also connected to many other brain regions that mediate those same …

Coordinated drift of receptive fields in Hebbian/anti-Hebbian network models during noisy representation learning

S Qin, S Farashahi, D Lipshutz, AM Sengupta… - Nature …, 2023 - nature.com
Recent experiments have revealed that neural population codes in many brain areas
continuously change even when animals have fully learned and stably perform their tasks …

[HTML][HTML] Play and tickling responses map to the lateral columns of the rat periaqueductal gray

N Gloveli, J Simonnet, W Tang, M Concha-Miranda… - Neuron, 2023 - cell.com
The persistence of play after decortication points to a subcortical mechanism of play control.
We found that global blockade of the rat periaqueductal gray with either muscimol or …

Tracking neurons across days with high-density probes

EH van Beest, C Bimbard, JMJ Fabre, SW Dodgson… - Nature …, 2024 - nature.com
Neural activity spans multiple time scales, from milliseconds to months. Its evolution can be
recorded with chronic high-density arrays such as Neuropixels probes, which can measure …

Learning-induced changes in the neural circuits underlying motor sequence execution

NK Harpaz, K Hardcastle, BP Ölveczky - Current opinion in neurobiology, 2022 - Elsevier
As the old adage goes: practice makes perfect. Yet, the neural mechanisms by which rote
repetition transforms a halting behavior into a fluid, effortless, and “automatic” action are not …

Metal microdrive and head cap system for silicon probe recovery in freely moving rodent

M Vöröslakos, PC Petersen, B Vöröslakos, G Buzsáki - Elife, 2021 - elifesciences.org
High-yield electrophysiological extracellular recording in freely moving rodents provides a
unique window into the temporal dynamics of neural circuits. Recording from unrestrained …

[HTML][HTML] From innate to instructed: A new look at perceptual decision-making

LT Oesch, MB Ryan, AK Churchland - Current Opinion in Neurobiology, 2024 - Elsevier
Understanding how subjects perceive sensory stimuli in their environment and use this
information to guide appropriate actions is a major challenge in neuroscience. To study …