The BioPAX community standard for pathway data sharing

E Demir, MP Cary, S Paley, K Fukuda, C Lemer… - Nature …, 2010 - nature.com
Abstract Biological Pathway Exchange (BioPAX) is a standard language to represent
biological pathways at the molecular and cellular level and to facilitate the exchange of …

Minimum information requested in the annotation of biochemical models (MIRIAM)

NL Novère, A Finney, M Hucka, US Bhalla… - Nature …, 2005 - nature.com
Most of the published quantitative models in biology are lost for the community because they
are either not made available or they are insufficiently characterized to allow them to be …

DeepPPI: boosting prediction of protein–protein interactions with deep neural networks

X Du, S Sun, C Hu, Y Yao, Y Yan… - Journal of chemical …, 2017 - ACS Publications
The complex language of eukaryotic gene expression remains incompletely understood.
Despite the importance suggested by many proteins variants statistically associated with …

From genomics to proteomics

M Tyers, M Mann - Nature, 2003 - nature.com
Proteomics is the study of the function of all expressed proteins. Tremendous progress has
been made in the past few years in generating large-scale data sets for protein–protein …

BIND: the biomolecular interaction network database

GD Bader, D Betel, CWV Hogue - Nucleic acids research, 2003 - academic.oup.com
Abstract The Biomolecular Interaction Network Database (BIND: http://bind. ca) archives
biomolecular interaction, complex and pathway information. A web-based system is …

Global analysis of protein phosphorylation in yeast

J Ptacek, G Devgan, G Michaud, H Zhu, X Zhu… - Nature, 2005 - nature.com
Protein phosphorylation is estimated to affect 30% of the proteome and is a major regulatory
mechanism that controls many basic cellular processes,,. Until recently, our biochemical …

iRefIndex: a consolidated protein interaction database with provenance

S Razick, G Magklaras, IM Donaldson - BMC bioinformatics, 2008 - Springer
Background Interaction data for a given protein may be spread across multiple databases.
We set out to create a unifying index that would facilitate searching for these data and that …

Relating whole-genome expression data with protein-protein interactions

R Jansen, D Greenbaum, M Gerstein - Genome research, 2002 - genome.cshlp.org
We investigate the relationship of protein-protein interactions with mRNA expression levels,
by integrating a variety of data sources for yeast. We focus on known protein complexes that …

Exploiting indirect neighbours and topological weight to predict protein function from protein–protein interactions

HN Chua, WK Sung, L Wong - Bioinformatics, 2006 - academic.oup.com
Motivation: Most approaches in predicting protein function from protein–protein interaction
data utilize the observation that a protein often share functions with proteins that interacts …

The HUPO PSI's molecular interaction format—a community standard for the representation of protein interaction data

H Hermjakob, L Montecchi-Palazzi, G Bader… - Nature …, 2004 - nature.com
A major goal of proteomics is the complete description of the protein interaction network
underlying cell physiology. A large number of small scale and, more recently, large-scale …