Unveiling the Nutritional Veil of Sulforaphane: With a Major Focus on Glucose Homeostasis Modulation

Y Wang, X He, N Cheng, K Huang - Nutrients, 2024 - mdpi.com
Abnormal glucose homeostasis is associated with metabolic syndromes including
cardiovascular diseases, hypertension, type 2 diabetes mellitus, and obesity, highlighting …

[HTML][HTML] Activation of Nrf2 and FXR via Natural Compounds in Liver Inflammatory Disease

M Belka, A Gostyńska-Stawna, M Stawny… - International Journal of …, 2024 - mdpi.com
Liver inflammation is frequently linked to oxidative stress and dysregulation of bile acid and
fatty acid metabolism. This review focuses on the farnesoid X receptor (FXR), a critical …

6-Pentyl-α-Pyrone from Trichoderma gamsii Exert Antioxidant and Anti-Inflammatory Properties in Lipopolysaccharide-Stimulated Mouse Macrophages

JS Lim, JH Hong, DY Lee, X Li, DE Lee, JU Choi… - Antioxidants, 2023 - mdpi.com
Filamentous fungi produce several beneficial secondary metabolites, including bioactive
compounds, food additives, and biofuels. Trichoderma, which is a teleomorphic Hypocrea …

Cannabis sativa (Hemp) seed-derived peptides WVYY and PSLPA modulate the Nrf2 signaling pathway in human keratinocytes

E Kim, J Jang, HH Seo, JH Lee, SH Moh - Plos one, 2024 - journals.plos.org
Cannabis sativa (Hemp) seeds are used widely for cosmetic and therapeutic applications,
and contain peptides with substantial therapeutic potential. Two key peptides, WVYY and …

The Immunoregulatory and Regenerative Potential of Activated Human Stem Cell Secretome Mitigates Acute-on-Chronic Liver Failure in a Rat Model

B Cuadra, V Silva, YL Huang, Y Diaz, C Rivas… - International Journal of …, 2024 - mdpi.com
Acute-on-chronic liver failure (ACLF) is a syndrome marked by sudden liver function decline
and multiorgan failure, predominantly acute kidney injury (AKY), in patients with chronic liver …

Silymarin Synergizes with Antiviral Therapy in Hepatitis B Virus-Related Liver Cirrhosis: A Propensity Score Matching Multi-Institutional Study

CH Huang, VCC Wu, CL Wang, CL Wu… - International Journal of …, 2024 - mdpi.com
Hepatitis B virus (HBV)-related liver cirrhosis (HBV-LC) presents a substantial mortality and
hepatocellular carcinoma (HCC) risk. While antiviral therapy (AVT) is the standard, complete …

Protective effects of Huang-Qi-Ge-Gen decoction against diabetic liver injury through regulating PI3K/AKT/Nrf2 pathway and metabolic profiling

ZT Zhang, QF Liang, X Wang, RS Wang… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Huang-Qi-Ge-Gen decoction (HGD) is a
traditional Chinese medicine prescription that has been used for centuries to treat …

Melissa officinalis extract palliates redox imbalance and inflammation associated with hyperthyroidism-induced liver damage by regulating Nrf-2/ Keap-1 gene …

RSM Kawara, FSM Moawed, Y Elsenosi… - … Medicine and Therapies, 2024 - Springer
Background Melissa officinalis (MO) is a well-known medicinal plant species used in the
treatment of several diseases; it is widely used as a vegetable, adding flavour to dishes. This …

[HTML][HTML] Regulation of Nrf2/Keap1 signaling pathway in cancer drug resistance by galectin-1: cellular and molecular implications

İ Yaylim, M Aru, AA Farooqi, MT Hakan… - Cancer Drug …, 2024 - ncbi.nlm.nih.gov
Oxidative stress is characterized by the deregulation of the redox state in the cells, which
plays a role in the initiation of various types of cancers. The activity of galectin-1 (Gal-1) …

A potential therapeutic impact of Gallic acid in a rat model of hepatocarcinogenesis through inhibition of cell proliferation and oncogenic miRNA-221 and induction of …

AES Al-Semelawy, SA Aziza, A El-Maksoud… - Benha Veterinary …, 2024 - journals.ekb.eg
Hepatocellular carcinoma (HCC) is still a main cause of fatality for individuals with chronic
liver illnesses, according to statistical analyses of cancer. Gallic acid (GA) is among the most …