[HTML][HTML] An in silico deep learning approach to multi-epitope vaccine design: a SARS-CoV-2 case study

Z Yang, P Bogdan, S Nazarian - Scientific reports, 2021 - nature.com
The rampant spread of COVID-19, an infectious disease caused by SARS-CoV-2, all over
the world has led to over millions of deaths, and devastated the social, financial and political …

Pathophysiologic mechanisms of cerebral endotheliopathy and stroke due to Sars-CoV-2

V Kakarla, N Kaneko, M Nour… - Journal of Cerebral …, 2021 - journals.sagepub.com
Cerebrovascular events have emerged as a central feature of the clinical syndrome
associated with Sars-CoV-2 infection. This increase in infection-related strokes is marked by …

[HTML][HTML] Should we discount the laboratory origin of COVID-19?

R Segreto, Y Deigin, K McCairn, A Sousa… - Environmental chemistry …, 2021 - Springer
There is a near-consensus view that severe acute respiratory syndrome coronavirus (SARS-
CoV-2), the causative agent of COVID-19, has a natural zoonotic origin; however, several …

[HTML][HTML] Fibrinolytic system and COVID-19: From an innovative view of epithelial ion transport

Y Fu, H Xue, T Wang, Y Ding, Y Cui, H Nie - Biomedicine & …, 2023 - Elsevier
Lifeways of worldwide people have changed dramatically amid the coronavirus disease
2019 (COVID-19) pandemic, and public health is at stake currently. In the early stage of …

[HTML][HTML] Urokinase system in pathogenesis of pulmonary fibrosis: A hidden threat of COVID-19

AA Shmakova, VS Popov, IP Romanov… - International Journal of …, 2023 - mdpi.com
Pulmonary fibrosis is a common and threatening post-COVID-19 complication with poorly
resolved molecular mechanisms and no established treatment. The plasminogen activator …

[HTML][HTML] Consensus docking and MM-PBSA computations identify putative furin protease inhibitors for developing potential therapeutics against COVID-19

B Dankwa, E Broni, KS Enninful, SK Kwofie… - Structural Chemistry, 2022 - Springer
Abstract The coronavirus disease 2019 (COVID-19) is a pandemic that has severely posed
substantial health challenges and claimed millions of lives. Though vaccines have been …

Structure-based virtual screening methods for the identification of novel phytochemical inhibitors targeting furin protease for the management of COVID-19

P Kumar Tiwari, M Chouhan, R Mishra… - Frontiers in Cellular …, 2024 - frontiersin.org
The coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) virus, is a highly contagious respiratory disease with …

[HTML][HTML] The Association of PLAUR Genotype and Soluble suPAR Serum Level with COVID-19-Related Lung Damage Severity

LA Nekrasova, AA Shmakova… - International Journal of …, 2022 - mdpi.com
Uncovering the risk factors for acute respiratory disease coronavirus 2019 (COVID-19)
severity may help to provide a valuable tool for early patient stratification and proper …

[PDF][PDF] Development of a multi-epitope spike glycoprotein vaccine to combat SARS-CoV-2 using the bioinformatics approach

A Shehzad, C Sumartono, J Nugraha… - J. Pharm. Pharmacogn …, 2022 - academia.edu
Context: The current COVID-19 pandemic has significantly impacted health and socio-
economic status worldwide. The only way to combat this situation is to develop an effective …

Vaccines efficacy to SARS-CoV-2 variants require holistic knowledge of viral immunology and protein biochemistry

S Kumar - Human Vaccines & Immunotherapeutics, 2021 - Taylor & Francis
The article by Abdalla et al., published in the journal on 28 May 2021, raised a concern. The
SARS-CoV-2 spike (S) protein is the major targeted surface glycoprotein in COVID-19 …