The role of the EBV-encoded latent membrane proteins LMP1 and LMP2 in the pathogenesis of nasopharyngeal carcinoma (NPC)

CW Dawson, RJ Port, LS Young - Seminars in cancer biology, 2012 - Elsevier
Although frequently expressed in EBV-positive malignancies, the contribution of the
oncogenic latent membrane proteins, LMP1 and LMP2, to the pathogenesis of …

Nasopharyngeal carcinoma: the next challenges

ARA Razak, LL Siu, FF Liu, E Ito, B O'Sullivan… - European journal of …, 2010 - Elsevier
Nasopharyngeal carcinoma (NPC) differs from other head and neck cancers in its aetiology,
epidemiology and potential therapeutic options. Despite cure for the majority of the patients …

[HTML][HTML] EBV-driven LMP1 and IFN-γ up-regulate PD-L1 in nasopharyngeal carcinoma: Implications for oncotargeted therapy

W Fang, J Zhang, S Hong, J Zhan, N Chen, T Qin… - Oncotarget, 2014 - ncbi.nlm.nih.gov
PD-L1 expression is a feature of Epstein-Barr virus (EBV) associated malignancies such as
nasopharyngeal carcinoma (NPC). Here, we found that EBV-induced latent membrane …

Targeting Epstein–Barr virus oncoprotein LMP1-mediated glycolysis sensitizes nasopharyngeal carcinoma to radiation therapy

L Xiao, ZY Hu, X Dong, Z Tan, W Li, M Tang, L Chen… - Oncogene, 2014 - nature.com
Our goal in this work was to illustrate the Epstein-Barr virus (EBV)-modulated global
biochemical profile and provide a novel metabolism-related target to improve the therapeutic …

Prevotella as the hub of the cervicovaginal microbiota affects the occurrence of persistent human papillomavirus infection and cervical lesions in women of …

B Dong, Y Huang, H Cai, Y Chen, Y Li… - Journal of Medical …, 2022 - Wiley Online Library
There is evidence that coinfection of cervicovaginal high‐risk human papillomavirus (HR‐
HPV) and bacteria is common in women of childbearing age. However, the relationship …

Tumour inflammasome‐derived IL‐1β recruits neutrophils and improves local recurrence‐free survival in EBV‐induced nasopharyngeal carcinoma

LC Chen, LJ Wang, NM Tsang, DM Ojcius… - EMBO molecular …, 2012 - embopress.org
Inflammasomes sense infection and cellular damage and are critical for triggering
inflammation through IL‐1β production. In carcinogenesis, inflammasomes may have …

miR-200a-mediated downregulation of ZEB2 and CTNNB1 differentially inhibits nasopharyngeal carcinoma cell growth, migration and invasion

H Xia, SS Ng, S Jiang, WKC Cheung, J Sze… - Biochemical and …, 2010 - Elsevier
Nasopharyngeal carcinoma (NPC), a highly metastatic and invasive malignant tumor
originating from the nasopharynx, is widely prevalent in Southeast Asia, the Middle East and …

The role of Epstein-Barr virus infection in the pathogenesis of nasopharyngeal carcinoma

CM Tsang, SW Tsao - Virologica Sinica, 2015 - Springer
Nasopharyngeal carcinoma (NPC) is closely associated with Epstein-Barr virus (EBV)
infection. EBV episomes are detected in almost all NPC cells. The role of EBV in NPC …

Epstein-Barr nuclear antigen 1 contributes to nasopharyngeal carcinoma through disruption of PML nuclear bodies

N Sivachandran, F Sarkari, L Frappier - PLoS pathogens, 2008 - journals.plos.org
Latent Epstein-Barr virus (EBV) infection is strongly associated with several cancers,
including nasopharyngeal carcinoma (NPC), a tumor that is endemic in several parts of the …

Epstein-Barr virus mediated signaling in nasopharyngeal carcinoma carcinogenesis

T Richardo, P Prattapong, C Ngernsombat… - Cancers, 2020 - mdpi.com
Simple Summary Epstein-Barr virus (EBV) infection is known to contribute in
nasopharyngeal carcinoma (NPC) carcinogenesis. The oncogenic roles of the EBV proteins …