The existence of small-molecule signals that influence development in Caenorhabditis
elegans has been known for several decades, but only in recent years have the chemical …

The nematode Caenorhabditis elegans produces tens, if not hundreds, of different
ascarosides as pheromones to communicate with other members of its species. Overlapping …

Peroxisomal β-oxidation (pβo) is a highly conserved fat metabolism pathway involved in the
biosynthesis of diverse signaling molecules in animals and plants. In Caenorhabditis …

A lack of appropriate molecular tools is one obstacle that prevents in-depth mechanistic
studies in many organisms. Transgenesis, clustered regularly interspaced short palindromic …

Many bacterivorous and parasitic nematodes secrete signaling molecules called
ascarosides that play a central role regulating their behavior and development. Combining …

Small-molecule signaling in nematode dauer formation has emerged as a major model to
study chemical communication in development and evolution. Developmental arrest as …

Covering: up to 2015 The nematode Caenorhabditis elegans was the first animal to have its
genome fully sequenced and has become an important model organism for biomedical …

Nematodes such as Caenorhabditis elegans are powerful systems to study basically all
aspects of biology. Their species richness together with tremendous genetic knowledge from …

The global efforts for onchocerciasis elimination may require additional tools (safe micro and
macrofilaricidal drugs, vaccines and biomarkers) as elimination efforts move toward the “end …

The small molecules that mediate chemical communication between nematodes—so-called
'nematode-derived-modular-metabolites'(NDMMs)—are of major interest because of their …