Biomaterials for intervertebral disc regeneration and repair
The intervertebral disc contributes to motion, weight bearing, and flexibility of the spine, but
is susceptible to damage and morphological changes that contribute to pathology with age …
is susceptible to damage and morphological changes that contribute to pathology with age …
Mechanobiology of annulus fibrosus and nucleus pulposus cells in intervertebral discs
S Molladavoodi, J McMorran, D Gregory - Cell and Tissue Research, 2020 - Springer
Low back pain (LBP) is a chronic condition that can affect up to 80% of the global
population. It is the number one cause of disability worldwide and has enormous …
population. It is the number one cause of disability worldwide and has enormous …
Current strategies for treatment of intervertebral disc degeneration: substitution and regeneration possibilities
Background Intervertebral disc degeneration has an annual worldwide socioeconomic
impact masked as low back pain of over 70 billion euros. This disease has a high …
impact masked as low back pain of over 70 billion euros. This disease has a high …
[HTML][HTML] Silk: a promising biomaterial opening new vistas towards affordable healthcare solutions
Substantial progress in biomaterial research over the years has culminated in revolutionary
technological advancements in the healthcare domain. This has triggered the quest for …
technological advancements in the healthcare domain. This has triggered the quest for …
[PDF][PDF] Polysaccharides as cell carriers for tissue engineering: the use of cellulose in vascular wall reconstruction
L Bacakova, K Novotná, M Parizek - Physiological Research, 2014 - biomed.cas.cz
Polysaccharides are long carbohydrate molecules of monosaccharide units joined together
by glycosidic bonds. These biological polymers have emerged as promising materials for …
by glycosidic bonds. These biological polymers have emerged as promising materials for …
[HTML][HTML] Strategies for annulus fibrosus regeneration: from biological therapies to tissue engineering
G Chu, C Shi, H Wang, W Zhang, H Yang… - … in bioengineering and …, 2018 - frontiersin.org
Intervertebral disc (IVD) is an avascular tissue which contributes to the weight bearing,
motion, and flexibility of spine. However, IVD is susceptible to damage and even failure due …
motion, and flexibility of spine. However, IVD is susceptible to damage and even failure due …
The nucleus pulposus microenvironment in the intervertebral disc: the fountain of youth?
The intervertebral disc (IVD) is a complex tissue, and its degeneration remains a problem for
patients, without significant improvement in treatment strategies. This mostly age-related …
patients, without significant improvement in treatment strategies. This mostly age-related …
Silk fibroin scaffolds for common cartilage injuries: possibilities for future clinical applications
Regenerating chondral and osteochondral injuries is a main challenge in orthopedics.
Some therapeutic strategies such as joint preservation operations, non-operative …
Some therapeutic strategies such as joint preservation operations, non-operative …
Tissue‐engineered cartilage: The crossroads of biomaterials, cells and stimulating factors
N Bhardwaj, D Devi, BB Mandal - Macromolecular bioscience, 2015 - Wiley Online Library
Damage to cartilage represents one of the most challenging tasks of musculoskeletal
therapeutics due to its limited propensity for healing and regenerative capabilities. Lack of …
therapeutics due to its limited propensity for healing and regenerative capabilities. Lack of …
Long-term mechanical function and integration of an implanted tissue-engineered intervertebral disc
Tissue engineering holds great promise for the treatment of advanced intervertebral disc
degeneration. However, assessment of in vivo integration and mechanical function of tissue …
degeneration. However, assessment of in vivo integration and mechanical function of tissue …