Longitudinal studies are mandatory to study aging, however, they have certain drawbacks,
for example, they require strict maintenance that is expensive given the breeding time …

While endocrine therapy is considered as an effective way to treat breast cancer, it still faces
many challenges, such as drug resistance and individual discrepancy. Therefore, novel …

Intervertebral disc degeneration (IVDD) is a complex process involving many factors, among
which excessive senescence of nucleus pulposus cells is considered to be the main factor …

Senescent microglia are a distinct microglial phenotype present in aging brain that have
been implicated in the progression of aging and age-related neurodegenerative diseases …

Premature ovarian failure (POF) is a leading cause of infertility in women, causing significant
psychological and physical distress. Current therapeutic options are limited, necessitating …

Cardiovascular disease (CVD) is highly prevalent in an ageing society. The increased
incidence and mortality rates of CVD are global issues endangering human health. There is …

Mesenchymal stem cells (MSCs) can be used as a cell source for cultivated meat production
due to their adipose differentiation potential, but MSCs lose their stemness and undergo …

Aging has been deemed the primary factor in erectile dysfunction (ED). Herein, age‐related
changes in the erectile response and histomorphology were detected, and the relationship …

Terpenoids are a wide class of secondary metabolites with geroprotective properties that
can alter the mechanism of aging and aging-related diseases. Camphorquinone (CQ) is a …

Non-alcoholic fatty liver disease is characterized by disturbed lipid metabolism and
increased oxidative stress. These conditions lead to the activation of different cellular …