Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …

Drug resistance represents a major obstacle in cancer management, and the mechanisms
underlying stress adaptation of cancer cells in response to therapy-induced hostile …

Pyroptosis, as a novel mode of cell death, has been proven to have impressive antitumor
effects. Dying cells undergoing pyroptosis can elicit antitumor immunity by the release of …

Recently, lactate has been considered as an alternative direct energy substance to glucose
for tumor proliferation and metastasis. Meanwhile, mitochondria, as important energy …

Chemo‐phototherapy has emerged as a promising approach to complement traditional
cancer treatment and enhance therapeutic effects. However, it still faces the challenges of …

Cancer treatment is hampered by resistance to conventional therapeutic strategies,
including chemotherapy, immunotherapy, and targeted therapy. Redox homeostasis …

Nanomedicine application in cancer therapy is an urgency because of inability of current
biological therapies for complete removal of tumor cells. The development of smart and …

Mitochondria are the primary source of energy production in neurons, supporting the high
energy consumption of the nervous system. Inefficient and dysfunctional mitochondria in the …

Colorectal cancer (CRC) is the second most deadly cancer worldwide, with
chemoresistance remaining a major obstacle in CRC treatment. Sodium persulfate (Na 2 S 2 …

Dormancy occurs when cells preserve viability but stop proliferating, which is considered an
important cause of tumor relapse, which may occur many years after clinical remission …