Phenotypic impact of genomic structural variation: insights from and for human disease
J Weischenfeldt, O Symmons, F Spitz… - Nature Reviews …, 2013 - nature.com
Genomic structural variants have long been implicated in phenotypic diversity and human
disease, but dissecting the mechanisms by which they exert their functional impact has …
disease, but dissecting the mechanisms by which they exert their functional impact has …
[HTML][HTML] Breeding for resistance to gastrointestinal nematodes–the potential in low-input/output small ruminant production systems
The control of gastrointestinal nematodes (GIN) is mainly based on the use of drugs, grazing
management, use of copper oxide wire particles and bioactive forages. Resistance to …
management, use of copper oxide wire particles and bioactive forages. Resistance to …
Genotyping-by-sequencing (GBS): a novel, efficient and cost-effective genotyping method for cattle using next-generation sequencing
High-throughput genotyping methods have increased the analytical power to study complex
traits but high cost has remained a barrier for large scale use in animal improvement. We …
traits but high cost has remained a barrier for large scale use in animal improvement. We …
Structural variants in the soybean genome localize to clusters of biotic stress-response genes
LK McHale, WJ Haun, WW Xu, PB Bhaskar… - Plant …, 2012 - academic.oup.com
Genome-wide structural and gene content variations are hypothesized to drive important
phenotypic variation within a species. Structural and gene content variations were assessed …
phenotypic variation within a species. Structural and gene content variations were assessed …
Transcriptional profiling of mammary gland in Holstein cows with extremely different milk protein and fat percentage using RNA sequencing
X Cui, Y Hou, S Yang, Y Xie, S Zhang, Y Zhang… - BMC genomics, 2014 - Springer
Abstract Background Recently, RNA sequencing (RNA-seq) has rapidly emerged as a major
transcriptome profiling system. Elucidation of the bovine mammary gland transcriptome by …
transcriptome profiling system. Elucidation of the bovine mammary gland transcriptome by …
Insights into genetic diversity, runs of homozygosity and heterozygosity-rich regions in Maremmana semi-feral cattle using pedigree and genomic data
Simple Summary In this study, we estimated genetic diversity in semi-feral Maremmana
cattle using both pedigree-and genomic-based approaches, and detected regions of …
cattle using both pedigree-and genomic-based approaches, and detected regions of …
Genome-wide detection of copy number variations using high-density SNP genotyping platforms in Holsteins
Abstract Background Copy number variations (CNVs) are widespread in the human or
animal genome and are a significant source of genetic variation, which has been …
animal genome and are a significant source of genetic variation, which has been …
Genome wide CNV analysis reveals additional variants associated with milk production traits in Holsteins
Background Milk production is an economically important sector of global agriculture. Much
attention has been paid to the identification of quantitative trait loci (QTL) associated with …
attention has been paid to the identification of quantitative trait loci (QTL) associated with …
CNV discovery for milk composition traits in dairy cattle using whole genome resequencing
Y Gao, J Jiang, S Yang, Y Hou, GE Liu, S Zhang… - BMC genomics, 2017 - Springer
Abstract Background Copy number variations (CNVs) are important and widely distributed in
the genome. CNV detection opens a new avenue for exploring genes associated with …
the genome. CNV detection opens a new avenue for exploring genes associated with …
Genome-wide study of structural variants in bovine Holstein, Montbéliarde and Normande dairy breeds
High-throughput sequencing technologies have offered in recent years new opportunities to
study genome variations. These studies have mostly focused on single nucleotide …
study genome variations. These studies have mostly focused on single nucleotide …