Cancer vaccines and carbohydrate epitopes

J Heimburg-Molinaro, M Lum, G Vijay, M Jain… - Vaccine, 2011 - Elsevier
Tumor-associated carbohydrate antigens (TACA) result from the aberrant glycosylation that
is seen with transformation to a tumor cell. The carbohydrate antigens that have been found …

Dendrimers toward translational nanotherapeutics: concise key step analysis

S Mignani, X Shi, J Rodrigues, R Roy… - Bioconjugate …, 2020 - ACS Publications
The goal of nanomedicine is to address specific clinical problems optimally, to fight human
diseases, and to find clinical relevance to change clinical practice. Nanomedicine is poised …

Phage display-based nanotechnology applications in cancer immunotherapy

M Goracci, Y Pignochino, S Marchiò - Molecules, 2020 - mdpi.com
Phage display is a nanotechnology with limitless potential, first developed in 1985 and still
awaiting to reach its peak. Awarded in 2018 with the Nobel Prize for Chemistry, the method …

Inhibition of prostate cancer bone metastasis by synthetic TF antigen mimic/galectin-3 inhibitor lactulose-L-leucine

OV Glinskii, S Sud, VV Mossine, TP Mawhinney… - Neoplasia, 2012 - Elsevier
Currently incurable, prostate cancer metastasis has a remarkable ability to spread to the
skeleton. Previous studies demonstrated that interactions mediated by the cancer …

The role of components of Bifidobacterium and Lactobacillus in pathogenesis and serologic diagnosis of autoimmune thyroid diseases

E Kiseleva, K Mikhailopulo, O Sviridov… - Beneficial …, 2011 - wageningenacademic.com
During recent years, researchers have been focusing on the concept of an infectious
etiology of autoimmune diseases. The most discussed theory is molecular mimicry, ie the …

Galectin-3 and epithelial MUC1 mucin—interactions supporting cancer development

I Radziejewska - Cancers, 2023 - mdpi.com
Simple Summary MUC1 mucin with T antigen and galectin-3 with high affinity to T
disaccharide are both overexpressed in a variety of human cancers. Their mutual …

Glycodendrimers as functional antigens and antitumor vaccines

TC Shiao, R Roy - New Journal of Chemistry, 2012 - pubs.rsc.org
Glycodendrimers have advantageous characteristics of providing potent immunostimulating
and adjuvant properties in vaccine preparation due to their molecularly defined multivalent …

Design, synthetic strategies, and therapeutic applications of heterofunctional glycodendrimers

L Mousavifar, R Roy - Molecules, 2021 - mdpi.com
Glycodendrimers have attracted considerable interest in the field of dendrimer sciences
owing to their plethora of implications in biomedical applications. This is primarily due to the …

Interaction of the oncofetal Thomsen–Friedenreich antigen with galectins in cancer progression and metastasis

P Sindrewicz, LY Lian, LG Yu - Frontiers in oncology, 2016 - frontiersin.org
Aberrant glycosylation of cell membrane proteins is a universal feature of cancer cells. One
of the most common glycosylation changes in epithelial cancer is the increased occurrence …

Glycodendrimers: versatile tools for nanotechnology

R Roy, TC Shiao, K Rittenhouse-Olson - Brazilian Journal of …, 2013 - SciELO Brasil
Combining nanotechnology with glycobiology has triggered an exponential growth of
research activities in the design of novel functional bionanomaterials (glyconanotechnology) …