[HTML][HTML] Hydrogels for RNA delivery
RNA-based therapeutics have shown tremendous promise in disease intervention at the
genetic level, and some have been approved for clinical use, including the recent COVID-19 …
genetic level, and some have been approved for clinical use, including the recent COVID-19 …
The current state and future directions of RNAi-based therapeutics
The RNA interference (RNAi) pathway regulates mRNA stability and translation in nearly all
human cells. Small double-stranded RNA molecules can efficiently trigger RNAi silencing of …
human cells. Small double-stranded RNA molecules can efficiently trigger RNAi silencing of …
[HTML][HTML] Nanotechnology-based delivery of CRISPR/Cas9 for cancer treatment
Abstract CRISPR/Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats-
associated protein 9) is a potent technology for gene-editing. Owing to its high specificity …
associated protein 9) is a potent technology for gene-editing. Owing to its high specificity …
Natural polymers-based light-induced hydrogels: Promising biomaterials for biomedical applications
There has been a significant increase in demand for biomaterials over the last decades.
According to this fact, the design and development of more efficient and sophisticated …
According to this fact, the design and development of more efficient and sophisticated …
Recent progress on polysaccharide-based hydrogels for controlled delivery of therapeutic biomolecules
MI Rial-Hermida, A Rey-Rico… - ACS Biomaterials …, 2021 - ACS Publications
A plethora of applications using polysaccharides have been developed in recent years due
to their availability as well as their frequent nontoxicity and biodegradability. These polymers …
to their availability as well as their frequent nontoxicity and biodegradability. These polymers …
Engineered hydrogels in cancer therapy and diagnosis
M Sepantafar, R Maheronnaghsh, H Mohammadi… - Trends in …, 2017 - cell.com
Over the last decade, numerous investigations have attempted to clarify the intricacies of
tumor development to propose effective approaches for cancer treatment. Thanks to the …
tumor development to propose effective approaches for cancer treatment. Thanks to the …
Multifunctional smart hydrogels: Potential in tissue engineering and cancer therapy
X Li, X Su - Journal of Materials Chemistry B, 2018 - pubs.rsc.org
In recent years, clinical applications have been proposed for various hydrogel products.
Hydrogels can be derived from animal tissues, plant extracts and/or adipose tissue …
Hydrogels can be derived from animal tissues, plant extracts and/or adipose tissue …
Harnessing nucleic acids nanotechnology for bone/cartilage regeneration
Y Han, L Cao, G Li, F Zhou, L Bai, J Su - Small, 2023 - Wiley Online Library
The effective regeneration of weight‐bearing bone defects and critical‐sized cartilage
defects remains a significant clinical challenge. Traditional treatments such as autologous …
defects remains a significant clinical challenge. Traditional treatments such as autologous …
Bioactive factor delivery strategies from engineered polymer hydrogels for therapeutic medicine
Polymer hydrogels have been widely explored as therapeutic delivery matrices because of
their ability to present sustained, localized and controlled release of bioactive factors …
their ability to present sustained, localized and controlled release of bioactive factors …
[HTML][HTML] RNA-based scaffolds for bone regeneration: application and mechanisms of mRNA, miRNA and siRNA
Q Leng, L Chen, Y Lv - Theranostics, 2020 - ncbi.nlm.nih.gov
Abstract Globally, more than 1.5 million patients undergo bone graft surgeries annually, and
the development of biomaterial scaffolds that mimic natural bone for bone grafting remains a …
the development of biomaterial scaffolds that mimic natural bone for bone grafting remains a …