Cyclin-dependent kinases (CDKs) are involved in many crucial processes, such as cell cycle
and transcription, as well as communication, metabolism, and apoptosis. The kinases are …

Neurological disorders are a group of disorders with motor, sensory or cognitive damage,
caused by dysfunction of the central or peripheral nervous system. Cyclin-dependent …

Cyclin-dependent kinase 12 (CDK12) belongs to the cyclin-dependent kinase (CDK) family
of serine/threonine protein kinases that regulate transcriptional and post-transcriptional …

Cyclin-dependent kinases (CDKs) are a group of serine/threonine protein kinases and play
crucial roles in various cellular processes by regulating cell cycle and gene transcription …

Cyclin-dependent kinases (CDKs) are key regulators of both cell cycle progression and
transcription. Since dysregulation of CDKs is a frequently occurring event driving …

CDK12 is a cyclin-dependent kinase that plays critical roles in DNA replication, transcription,
mRNA splicing, and DNA damage repair. CDK12 genomic changes, including mutation …

Alternative splicing and polyadenylation represent two major steps in pre‐mRNA‐
processing, which ensure proper gene expression and diversification of human …

Recently, secreted microRNAs (miRNAs) have received a lot of attention since they may act
as autocrine factors. However, how secreted miRNAs influence embryonic development is …

The role of cyclin-dependent kinases (CDKs) that are ubiquitously expressed in the adult
nervous system remains unclear. Cdk12 is enriched in terminally differentiated neurons …

Congenital heart defects, dysmorphic facial features and intellectual developmental
disorders (CHDFIDD) syndrome in humans was recently associated with mutation in CDK13 …