Glutathione in the human brain: Review of its roles and measurement by magnetic resonance spectroscopy

CD Rae, SR Williams - Analytical biochemistry, 2017 - Elsevier
We review the transport, synthesis and catabolism of glutathione in the brain as well as its
compartmentation and biochemistry in different brain cells. The major reactions involving …

The lactate receptor, G‐protein‐coupled receptor 81/hydroxycarboxylic acid receptor 1: Expression and action in brain

C Morland, KH Lauritzen, M Puchades… - Journal of …, 2015 - Wiley Online Library
We have proposed that lactate is a “volume transmitter” in the brain and underpinned this by
showing that the lactate receptor, G‐protein‐coupled receptor 81 (GPR81, also known as …

Advanced processing and simulation of MRS data using the FID appliance (FID‐A)—an open source, MATLAB‐based toolkit

R Simpson, GA Devenyi, P Jezzard… - Magnetic resonance …, 2017 - Wiley Online Library
Purpose To introduce a new toolkit for simulation and processing of magnetic resonance
spectroscopy (MRS) data, and to demonstrate some of its novel features. Methods The FID …

Acute modulation of cortical glutamate and GABA content by physical activity

RJ Maddock, GA Casazza, DH Fernandez… - Journal of …, 2016 - Soc Neuroscience
Converging evidence demonstrates that physical activity evokes a brain state characterized
by distinctive changes in brain metabolism and cortical function. Human studies have shown …

Short-term monocular deprivation alters GABA in the adult human visual cortex

C Lunghi, UE Emir, MC Morrone, H Bridge - Current Biology, 2015 - cell.com
Neuroplasticity is a fundamental property of the nervous system that is maximal early in life,
within the critical period [1–3]. Resting GABAergic inhibition is necessary to trigger ocular …

Effects of serotonin 2A/1A receptor stimulation on social exclusion processing

KH Preller, T Pokorny, A Hock… - Proceedings of the …, 2016 - National Acad Sciences
Social ties are crucial for physical and mental health. However, psychiatric patients
frequently encounter social rejection. Moreover, an increased reactivity to social exclusion …

Test‐retest reproducibility of neurochemical profiles with short‐echo, single‐voxel MR spectroscopy at 3T and 7T

M Terpstra, I Cheong, T Lyu… - Magnetic resonance …, 2016 - Wiley Online Library
Purpose To determine the test‐retest reproducibility of neurochemical concentrations
obtained with a highly optimized, short‐echo, single‐voxel proton MR spectroscopy (MRS) …

Functional MRS studies of GABA and glutamate/Glx–A systematic review and meta-analysis

D Pasanta, JL He, T Ford, G Oeltzschner… - Neuroscience & …, 2023 - Elsevier
Functional magnetic resonance spectroscopy (fMRS) can be used to investigate
neurometabolic responses to external stimuli in-vivo, but findings are inconsistent. We …

Aerobic glycolysis during brain activation: adrenergic regulation and influence of norepinephrine on astrocytic metabolism

GA Dienel, NF Cruz - Journal of neurochemistry, 2016 - Wiley Online Library
Aerobic glycolysis occurs during brain activation and is characterized by preferential up‐
regulation of glucose utilization compared with oxygen consumption even though oxygen …

[HTML][HTML] Combined fMRI-MRS acquires simultaneous glutamate and BOLD-fMRI signals in the human brain

IB Ip, A Berrington, AT Hess, AJ Parker, UE Emir… - Neuroimage, 2017 - Elsevier
Combined fMRI-MRS is a novel method to non-invasively investigate functional activation in
the human brain using simultaneous acquisition of hemodynamic and neurochemical …