Perivascular spaces (PVS) and blood–brain barrier (BBB) disruption are two key features of
cerebral small vessel disease (cSVD) and neurodegenerative diseases that have been …

The neurovascular unit (NVU) is a complex structure that facilitates nutrient delivery and
metabolic waste clearance, forms the blood–brain barrier (BBB), and supports fluid …

Aims Alzheimer's disease (AD) is characterized by the accumulation of amyloid beta (A β) in
the brain. The deposition of A β is believed to initiate a detrimental cascade, including …

Cognitive decline covers a broad spectrum of disorders, not only resulting from brain
diseases but also from systemic diseases, which seriously influence the quality of life and …

We conducted a meta-analysis of randomized controlled trials investigating the effects of
aerobic exercise training (AET) lasting≥ 4 weeks on hippocampal volume and …

Blood–brain barrier (BBB) disruption may contribute to cognitive decline, but questions
remain whether this association is more pronounced for certain brain regions, such as the …

Introduction Post-traumatic hypopituitarism (PTHP) is a significant, but often neglected
consequence of traumatic brain injury (TBI). Research question We aimed to provide a …

DSC-MRI examination is one of the best methods of diagnosis for brain diseases. For this
purpose, the so-called perfusion parameters are defined, of which the most used are CBF …

High-fat diets (HFDs) have pervaded modern dietary habits, characterized by their excessive
saturated fat content and low nutritional value. Epidemiological studies have compellingly …

The hippocampus is a critical brain substrate for learning and memory; events that harm the
hippocampus can seriously impair mental and behavioral functioning. Hippocampal …