Molecular heterogeneity and immunosuppressive microenvironment in glioblastoma
Glioblastoma (GBM) is the most aggressive primary brain tumor in adults, with a poor
prognosis, despite surgical resection combined with radio-and chemotherapy. The major …
prognosis, despite surgical resection combined with radio-and chemotherapy. The major …
Small interfering RNA (siRNA) to target genes and molecular pathways in glioblastoma therapy: Current status with an emphasis on delivery systems
Glioblastoma multiforme (GBM) is one of the worst brain tumors arising from glial cells,
causing many deaths annually. Surgery, chemotherapy, radiotherapy and immunotherapy …
causing many deaths annually. Surgery, chemotherapy, radiotherapy and immunotherapy …
Toll-like receptors and toll-like receptor-targeted immunotherapy against glioma
Y Xun, H Yang, B Kaminska, H You - Journal of hematology & oncology, 2021 - Springer
Glioma represents a fast proliferating and highly invasive brain tumor which is resistant to
current therapies and invariably recurs. Despite some advancements in anti-glioma …
current therapies and invariably recurs. Despite some advancements in anti-glioma …
Immunotherapy of glioblastoma: current strategies and challenges in tumor model development
Glioblastoma is the most common brain malignant tumor in the adult population, and
immunotherapy is playing an increasingly central role in the treatment of many cancers …
immunotherapy is playing an increasingly central role in the treatment of many cancers …
The role of cytokines and chemokines in shaping the immune microenvironment of glioblastoma: implications for immunotherapy
Glioblastoma is the most common form of primary brain tumour in adults. For more than a
decade, conventional treatment has produced a relatively modest improvement in the …
decade, conventional treatment has produced a relatively modest improvement in the …
Blood–brain barrier opening by intracarotid artery hyperosmolar mannitol induces sterile inflammatory and innate immune responses
SR Burks, CN Kersch, JA Witko… - Proceedings of the …, 2021 - National Acad Sciences
Intracarotid arterial hyperosmolar mannitol (ICAHM) blood–brain barrier disruption (BBBD)
is effective and safe for delivery of therapeutics for central nervous system malignancies …
is effective and safe for delivery of therapeutics for central nervous system malignancies …
Smart biomaterials to enhance the efficiency of immunotherapy in glioblastoma: State of the art and future perspectives
Glioblastoma multiform (GBM) is considered as the most lethal tumor among CNS
malignancies. Although immunotherapy has achieved remarkable advances in cancer …
malignancies. Although immunotherapy has achieved remarkable advances in cancer …
Critical view of novel treatment strategies for glioblastoma: failure and success of resistance mechanisms by glioblastoma cells
T Burster, R Traut, Z Yermekkyzy, K Mayer… - Frontiers in Cell and …, 2021 - frontiersin.org
According to the invasive nature of glioblastoma, which is the most common form of
malignant brain tumor, the standard care by surgery, chemo-and radiotherapy is particularly …
malignant brain tumor, the standard care by surgery, chemo-and radiotherapy is particularly …
[HTML][HTML] Recent treatment strategies and molecular pathways in resistance mechanisms of antiangiogenic therapies in glioblastoma
MA Rahman, MM Ali - Cancers, 2024 - mdpi.com
Simple Summary Glioblastoma (GBM) appears to be a challenging malignancy to
completely eradicate, with few significant improvements in treatment. This review explores …
completely eradicate, with few significant improvements in treatment. This review explores …
Dendritic cell vaccines improve the glioma microenvironment: Influence, challenges, and future directions
J Zhou, L Li, M Jia, Q Liao, G Peng, G Luo… - Cancer …, 2023 - Wiley Online Library
Introduction Gliomas, especially the glioblastomas, are one of the most aggressive
intracranial tumors with poor prognosis. This might be explained by the heterogeneity of …
intracranial tumors with poor prognosis. This might be explained by the heterogeneity of …