Sesamol, a major lignan in sesame seeds (Sesamum indicum): Anti-cancer properties and mechanisms of action

AF Majdalawieh, ZR Mansour - European journal of pharmacology, 2019 - Elsevier
Sesamol is a natural phenolic compound and a major lignan isolated from sesame seeds
(Sesamum indicum) and sesame oil. The therapeutic potential of sesamol was investigated …

[HTML][HTML] Resveratrol protects diabetic kidney by attenuating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via Nrf2–Keap1 signaling

P Palsamy, S Subramanian - … et Biophysica Acta (BBA)-Molecular Basis of …, 2011 - Elsevier
Hyperglycemia-mediated oxidative stress plays a crucial role in the progression of diabetic
nephropathy. Hence, the present study was hypothesized to explore the renoprotective …

Sesamol: A lignan in sesame seeds with potent anti-inflammatory and immunomodulatory properties

AF Majdalawieh, SH Ahari, SM Yousef… - European Journal of …, 2023 - Elsevier
Inflammation is associated with the development and progression of a plethora of diseases
including joint, metabolic, neurological, hepatic, and renal disorders. Sesamol, derived from …

Neutrophil-to-lymphocyte ratio as a predictor of worsening renal function in diabetic patients (3-year follow-up study)

B Azab, J Daoud, FB Naeem, R Nasr, J Ross… - Renal failure, 2012 - Taylor & Francis
Background: Previous studies have demonstrated the role of inflammation in diabetic
nephropathy (DN). Neutrophil to lymphocyte ratio (NLR) rather than other white cell …

Astragaloside IV ameliorates renal injury in streptozotocin-induced diabetic rats through inhibiting NF-κB-mediated inflammatory genes expression

D Gui, J Huang, Y Guo, J Chen, Y Chen, W Xiao, X Liu… - Cytokine, 2013 - Elsevier
Accumulating evidence suggests that inflammatory processes are involved in the
development of diabetic nephropathy (DN). However, there are no effective interventions for …

Anti-diabetic activity of chromium picolinate and biotin in rats with type 2 diabetes induced by high-fat diet and streptozotocin

K Sahin, M Tuzcu, C Orhan, N Sahin… - British Journal of …, 2013 - cambridge.org
The objective of the present study was to evaluate anti-diabetic effects of chromium
picolinate (CrPic) and biotin supplementations in type 2 diabetic rats. The type 2 diabetic rat …

Protective effect of ferulic acid and resveratrol against alloxan-induced diabetes in mice

M Ramar, B Manikandan, T Raman… - European Journal of …, 2012 - Elsevier
The present study was to investigate the effect of ferulic acid and resveratrol on alloxan-
induced diabetic mice, through analysis of basic biochemical parameters, enzymic as well …

Neuroprotective potential of sesamol and its loaded solid lipid nanoparticles in ICV-STZ-induced cognitive deficits: behavioral and biochemical evidence

AK Sachdeva, S Misra, IP Kaur, K Chopra - European journal of …, 2015 - Elsevier
Neuroinflammation is a prominent feature of Alzheimer disease (AD) and other chronic
neurodegenerative disorders. Intracerebroventricular (ICV) streptozotocin (STZ) induced …

Reversal of diabetes-induced behavioral and neurochemical deficits by cinnamaldehyde

A Jawale, AK Datusalia, M Bishnoi, SS Sharma - Phytomedicine, 2016 - Elsevier
Background Chronic hyperglycemia during diabetes is associated with altered cognitive
function. Cinnamaldehyde showed to have many pharmacological activities indicating anti …

Comparative hypoglycemic and nephroprotective effects of tocotrienol rich fraction (TRF) from palm oil and rice bran oil against hyperglycemia induced nephropathy in …

S Siddiqui, MR Khan, WA Siddiqui - Chemico-biological interactions, 2010 - Elsevier
Diabetic nephropathy (DN) is a serious complication confronted by patients with diabetes.
Available data indicate that the development of DN is linked to hyperglycemia. Tocotrienol …