Colorectal cancer is the leading cause of death from cancer globally. The current treatment
protocol still heavily relies on early detection and surgery. The molecular mechanisms …

Nitric oxide, carbon monoxide and hydrogen sulfide are three endogenous gasotransmitters
that serve a role in regulating normal and pathological cellular activities. They can stimulate …

Studies of rare genetic bone disorders are often limited due to unavailability of tissue
specimens and the lack of animal models fully replicating phenotypic features …

Stem cell technology can be used in tissue engineering and regenerative medicine to
transplant stem cells of somatic, embryonic, or induced pluripotent origin, which have …

The human induced pluripotent stem cell (hiPSC) provides a breakthrough approach that
helps overcoming ethical and allergenic challenges posed in application of neural stem …

The interaction between CD40 ligand (CD40L) and CD40 can directly inhibit growth of
CD40-positive carcinoma cells and may indirectly inhibit tumor growth through coordination …

Direct derivation of human induced pluripotent stem cells into neural precursor cells and
differentiation of these into neurons holds great promise in the cell therapy of …

Cell-based therapeutics have advanced significantly over the past decade and are poised to
become a major pillar of modern medicine. Three cell types in particular have been studied …

Recent progress in neural stem cell‐(NSC‐) based tumor‐targeted gene therapy showed
that NSC vectors expressing an artificially engineered viral fusogenic protein, VSV‐G …

Nitric oxide (NO) is a small free-radical gas molecule, which is highly diffusible and can
activate a wide range of downstream effectors, with rapid and widespread cellular effects …