Cancer immunoimaging with smart nanoparticles
Dynamic immunoimaging in vivo is crucial in patient-tailored immunotherapies to identify
patients who will benefit from immunotherapies, monitor therapeutic efficacy post treatment …
patients who will benefit from immunotherapies, monitor therapeutic efficacy post treatment …
In vivo imaging of nanoparticle-labeled CAR T cells
L Kiru, A Zlitni, AM Tousley, GN Dalton… - Proceedings of the …, 2022 - National Acad Sciences
Metastatic osteosarcoma has a poor prognosis with a 2-y, event-free survival rate of∼ 15 to
20%, highlighting the need for the advancement of efficacious therapeutics. Chimeric …
20%, highlighting the need for the advancement of efficacious therapeutics. Chimeric …
Emerging biomedical applications of polyaspartic acid-derived biodegradable polyelectrolytes and polyelectrolyte complexes
Polyelectrolytes (PELs)–polymers with charged repeat units–have emerged as a useful
class of polymers for biomedical applications due to their high aqueous solubility, low …
class of polymers for biomedical applications due to their high aqueous solubility, low …
Engineered exosomes with independent module/cascading function for therapy of Parkinson's disease by multistep targeting and multistage intervention method
Q Wang, T Li, J Yang, Z Zhao, K Tan, S Tang… - Advanced …, 2022 - Wiley Online Library
Current exosome engineering methods usually lead to the damage of exosome morphology
and membrane, which cannot meet the complex needs of disease treatment. Herein, the …
and membrane, which cannot meet the complex needs of disease treatment. Herein, the …
Engineering organic/inorganic nanohybrids through RAFT polymerization for biomedical applications
Despite many early accomplishments in nanomaterial design and synthesis, there remains a
significant requirement for novel inorganic and organic nanohybrids with the potential to act …
significant requirement for novel inorganic and organic nanohybrids with the potential to act …
Poly(amino acid) based fibrous membranes with tuneable in vivo biodegradation
In this work two types of biodegradable polysuccinimide-based, electrospun fibrous
membranes are presented. One contains disulfide bonds exhibiting a shorter (3 days) in vivo …
membranes are presented. One contains disulfide bonds exhibiting a shorter (3 days) in vivo …
Redox-responsive dextran based theranostic nanoparticles for near-infrared/magnetic resonance imaging and magnetically targeted photodynamic therapy
Photodynamic therapy (PDT) is a site-specific treatment of cancer using much lower optical
power densities with minimal nonspecific damage to normal tissues. To improve the …
power densities with minimal nonspecific damage to normal tissues. To improve the …
[HTML][HTML] Fully amino acid-based hydrogel as potential scaffold for cell culturing and drug delivery
Polymer hydrogels are ideal scaffolds for both tissue engineering and drug delivery. A great
advantage of poly (amino acid)-based hydrogels is their high similarity to natural proteins …
advantage of poly (amino acid)-based hydrogels is their high similarity to natural proteins …
Optical imaging of in vivo adoptive T‐cell therapy: State of the art and challenges
Adoptive T‐cell therapy (ACT), which is an important type of live cell therapy, has achieved
unprecedented success in treating hematological malignancies. Recent studies have shown …
unprecedented success in treating hematological malignancies. Recent studies have shown …
Bone targeting nano-aggregates prepared from self-assembled polyaspartamide graft copolymers for pH sensitive DOX delivery
C won Lim, D Kim - Biomaterials Science, 2021 - pubs.rsc.org
Nanoparticles with bone targeting ability and pH-sensitivity were prepared with
polyaspartamide (PASPAM) derivatives based on polysuccinimide (PSI) grafted with …
polyaspartamide (PASPAM) derivatives based on polysuccinimide (PSI) grafted with …