[HTML][HTML] Ocular surface allostasis—when homeostasis is lost: challenging coping potential, stress tolerance, and resilience

GB van Setten - Biomolecules, 2023 - mdpi.com
The loss of ocular surface (OS) homeostasis characterizes the onset of dry eye disease.
Resilience defines the ability to withstand this threat, reflecting the ability of the ocular …

[HTML][HTML] Enhancing detection accuracy via controlled release of 3D-printed microlattice nasopharyngeal swabs

R Xiao, J Li, YF Wong, LT Chu, Y Zhu, L Wang… - Communications …, 2024 - nature.com
Nasopharyngeal (NP) swab is one of the most effective sampling devices for clinical
specimens. However, commercial NP swabs often release samples through diluents …

[HTML][HTML] The Effect of High Molecular Weight Hyaluronic Acid and Latanoprost Eyedrops on Tear Functions and Ocular Surface Status in C57/BL6 Mice

M Dogru, T Kojima, K Higa, A Igarashi, H Kudo… - Journal of Clinical …, 2023 - mdpi.com
Anti-glaucoma eye drop treatment often induces ocular surface problems, including dry
eyes, and may be associated with poor medication compliance. This study aimed to …

Therapeutic Aqueous Humor Concentrations of Latanoprost Attained in Rats by Administration in a Very-High-Molecular-Weight Hyaluronic Acid Eye Drop

K Higa, R Kimoto, T Kojima, M Dogru… - Pharmaceutics, 2024 - mdpi.com
The temporal change in concentration of a novel medicine, Latanoprost (LP), was evaluated
in the aqueous humor of rats (6–8-week-old Jcl: Wister rats) when delivered in a very-high …

Application frequency–key indicator for the efficiency of severe dry eye disease treatment–evidence for the importance of molecular weight of hyaluronan in lubricating …

N Medic, I Boldin, B Berisha… - Acta …, 2023 - Wiley Online Library
Purpose Lubricant eye drops are the main therapeutic resource for dry eye disease (DED),
with each drop representing the equivalent of ocular surface disease treatment. Thus, any …

[HTML][HTML] The Influence of Tear Film Quality on Visual Function

S Kaštelan, K Gabrić, M Mikuličić, D Mrazovac Zimak… - Vision, 2024 - mdpi.com
Background: The prevalence of dry eye disease (DED) is increasing globally, resulting in a
variety of eye symptoms characterized by discomfort and visual disturbances. The accurate …

[HTML][HTML] Expression of GPR-68 in Human Corneal and Conjunctival Epithelium. Possible indicator and mediator of attrition associated inflammation at the ocular …

GB van Setten - Journal Français d'Ophtalmologie, 2023 - Elsevier
Introduction Attrition and osmotic stress have been identified as major forces in the
pathophysiology of dry eye. Impaired tolerance to mechano-transduction in the presence of …