Crosstalk between the circadian clock circuitry and the immune system
N Cermakian, T Lange, D Golombek… - Chronobiology …, 2013 - Taylor & Francis
Various features, components, and functions of the immune system present daily variations.
Immunocompetent cell counts and cytokine levels present variations according to the time of …
Immunocompetent cell counts and cytokine levels present variations according to the time of …
[HTML][HTML] Non-human primates as a model for aging
RJ Colman - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2018 - Elsevier
There has been, and continues to be, a dramatic shift in the human population towards older
ages necessitating biomedical research aimed at better understanding the basic biology of …
ages necessitating biomedical research aimed at better understanding the basic biology of …
Immune-Goblet cell interaction in the conjunctiva
J Alam, CS de Paiva, SC Pflugfelder - The ocular surface, 2020 - Elsevier
The conjunctiva is a goblet cell rich mucosal tissue. Goblet cells are supported by tear
growth factors and IL-13 produced by resident immune cells. Goblet cell secretions are …
growth factors and IL-13 produced by resident immune cells. Goblet cell secretions are …
The grey mouse lemur: a non-human primate model for ageing studies
The use of non-human primate models is required to understand the ageing process and
evaluate new therapies against age-associated pathologies. The present article summarizes …
evaluate new therapies against age-associated pathologies. The present article summarizes …
Influence of aging on Bmal1 and Per2 expression in extra-SCN oscillators in hamster brain
MJ Duncan, JR Prochot, DH Cook, JT Smith… - Brain research, 2013 - Elsevier
Deletion of the core clock gene, Bmal1, ablates circadian rhythms and accelerates aging,
leading to cognitive deficits and tissue atrophy (eg, skeletal muscle)(Kondratov et al., 2006 …
leading to cognitive deficits and tissue atrophy (eg, skeletal muscle)(Kondratov et al., 2006 …
Survival is reduced when endogenous period deviates from 24 h in a non-human primate, supporting the circadian resonance theory
C Hozer, M Perret, S Pavard, F Pifferi - Scientific Reports, 2020 - nature.com
Circadian rhythms are ubiquitous attributes across living organisms and allow the
coordination of internal biological functions with optimal phases of the environment …
coordination of internal biological functions with optimal phases of the environment …
Human African trypanosomiasis: How do the parasites enter and cause dysfunctions of the nervous system in murine models?
W Masocha, K Kristensson - Brain research bulletin, 2019 - Elsevier
In this review we describe how Trypanosoma brucei brucei, a rodent pathogenic strain of
African trypanosomes, can invade the nervous system, first by localization to the choroid …
African trypanosomes, can invade the nervous system, first by localization to the choroid …
Diurnal, age, and immune regulation of interleukin-1β and interleukin-1 type 1 receptor in the mouse suprachiasmatic nucleus
AL Beynon, AN Coogan - Chronobiology international, 2010 - Taylor & Francis
Circadian clocks serve to impose a near-24-h temporal architecture on an organism's
physiology, metabolism, and behavior. In mammals, the suprachiasmatic nucleus (SCN) of …
physiology, metabolism, and behavior. In mammals, the suprachiasmatic nucleus (SCN) of …
The biological clock in gray mouse lemur: adaptive, evolutionary and aging considerations in an emerging non-human primate model
C Hozer, F Pifferi, F Aujard, M Perret - Frontiers in Physiology, 2019 - frontiersin.org
Circadian rhythms, which measure time on a scale of 24 h, are genetically generated by the
circadian clock, which plays a crucial role in the regulation of almost every physiological and …
circadian clock, which plays a crucial role in the regulation of almost every physiological and …
Systemic and cellular reflections on ageing and the circadian oscillator–A mini-review
From circulation to digestion to excretion, a circadian clock synchronizes most aspects of
mammalian physiology with the solar day. During normal ageing, this daily coordination …
mammalian physiology with the solar day. During normal ageing, this daily coordination …