Developing strategies toward safe and effective drug delivery into the central nervous
system (CNS) with improved targeting abilities and reduced off-target effects is crucial. CNS …

Neurological disorders are diseases of the central nervous system (CNS), characterized by
a progressive degeneration of cells and deficiencies in neural functions. Mesenchymal stem …

Extracellular vesicles (EVs) have emerged as a promising strategy to promote tissue
regeneration. However, overcoming the low EV production yield remains a big challenge in …

Intravenous delivery of nanomaterials containing therapeutic agents and various cargos for
treating neurological disorders is often constrained by low delivery efficacy due to difficulties …

Tissue-specific uptake and sufficient biodistribution are central goals in drug development.
Crossing the blood–brain barrier (BBB) represents a major challenge in delivering …

Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized
by deficits in social communication, social interaction, and repetitive restricted behaviors …

Extracellular vesicles (EVs) are nanoscale particles with various physiological functions
including mediating cellular communication in the central nervous system (CNS), which …

Simple Summary A stroke occurs when there is a lack of blood flow to the brain. Stroke
injures the brain and can have devastating outcomes depending on the size and location of …

Exosomes are a subset of extracellular vesicles that act as messengers to facilitate
communication between cells. Non-coding RNAs, proteins, lipids, and microRNAs are …

The development and progression of autism spectrum disorder (ASD) is characterized by
multiple complex molecular events, highlighting the importance of the prefrontal brain …