To date, almost 2600 gene therapy clinical trials have been completed, are ongoing or have
been approved worldwide. Our database brings together global information on gene therapy …

Pluripotent stem cells (PSCs) hold great promise for drug discovery and regenerative
medicine owing to their ability to differentiate into any cell type in the body. After more than …

The increased risk of disease and decreased capacity to respond to tissue insult in the
setting of aging results from complex changes in homeostatic mechanisms, including the …

Pluripotent stem cells have the ability to undergo self‐renewal and to give rise to all cells of
the tissues of the body. However, this definition has been recently complicated by the …

Myocardial injury results in a loss of contractile tissue mass that, in the absence of efficient
regeneration, is essentially irreversible. Transplantation of human pluripotent stem cell …

In the past decades, continuous effort has been paid to deeply understanding the
pathophysiology of inflammatory bowel diseases (IBD), such as ulcerative colitis or Crohn's …

Anterior pituitary is critical for endocrine systems. Its hormonal responses to positive and
negative regulators are indispensable for homeostasis. For this reason, generating human …

Regenerative medicine, including preclinical studies in large animal models and tissue
engineering approaches as well as innovative assays for drug discovery, will require the …

Recent advances in the generation of cardiomyocytes (CMs) from human pluripotent stem
cells (hPSCs), in conjunction with the promising outcomes from preclinical and clinical …

Hematopoietic stem cell transplantation (HSCT) is the first field where human stem cell
therapy was successful. Flooding interest on human stem cell therapy to cure previously …