The RTS, S malaria vaccine

S Casares, TD Brumeanu, TL Richie - Vaccine, 2010 - Elsevier
RTS, S is the most advanced candidate vaccine against human malaria. During its
remarkable journey from conception and design in the early 1980s to the multicenter Phase …

Erythrocyte and reticulocyte binding-like proteins of Plasmodium falciparum

WH Tham, J Healer, AF Cowman - Trends in parasitology, 2012 - cell.com
The global agenda for malaria eradication would benefit from development of a highly
efficacious vaccine that protects against disease and interrupts transmission of Plasmodium …

Novel serologic biomarkers provide accurate estimates of recent Plasmodium falciparum exposure for individuals and communities

DA Helb, KKA Tetteh, PL Felgner… - Proceedings of the …, 2015 - National Acad Sciences
Tools to reliably measure Plasmodium falciparum (Pf) exposure in individuals and
communities are needed to guide and evaluate malaria control interventions. Serologic …

Potential contribution of sero‐epidemiological analysis for monitoring malaria control and elimination: historical and current perspectives

C Drakeley, J Cook - Advances in parasitology, 2009 - Elsevier
Anti‐malarial antibody responses represent an individual's history of exposure to the
disease and, as age sero‐conversion rates, reflect cumulative malaria exposure in a …

Advancements and challenges in developing malaria vaccines: Targeting multiple stages of the parasite life cycle

Rajneesh, R Tiwari, VK Singh, A Kumar… - ACS Infectious …, 2023 - ACS Publications
Malaria, caused by Plasmodium species, remains a major global health concern, causing
millions of deaths annually. While the introduction of the RTS, S vaccine has shown promise …

[HTML][HTML] Research priorities for the development and implementation of serological tools for malaria surveillance

SR Elliott, FJI Fowkes, JS Richards, L Reiling… - F1000prime …, 2014 - ncbi.nlm.nih.gov
Surveillance is a key component of control and elimination programs. Malaria surveillance
has been typically reliant on case reporting by health services, entomological estimates and …

Estimation of Recent and Long-Term Malaria Transmission in a Population by Antibody Testing to Multiple Plasmodium falciparum Antigens

BN Ondigo, JS Hodges, KF Ireland… - The Journal of …, 2014 - academic.oup.com
Background. Tools that estimate recent and long-term malaria transmission in a population
would be highly useful for malaria elimination programs. Methods. The prevalence of …

Identification of malaria transmission and epidemic hotspots in the western Kenya highlands: its application to malaria epidemic prediction

CL Wanjala, J Waitumbi, G Zhou, AK Githeko - Parasites & vectors, 2011 - Springer
Background Malaria in the western Kenya highlands is characterized by unstable and high
transmission variability which results in epidemics during periods of suitable climatic …

Naturally acquired immune responses against Plasmodium falciparum sporozoites and liver infection

V Offeddu, V Thathy, K Marsh… - International journal for …, 2012 - Elsevier
Malaria is a vector-borne infectious disease caused by infection with eukaryotic pathogens
termed Plasmodium. Epidemiological hallmarks of Plasmodium falciparum malaria are …

A venue-based survey of malaria, anemia and mobility patterns among migrant farm workers in Amhara Region, Ethiopia

RS Schicker, N Hiruy, B Melak, W Gelaye, B Bezabih… - PloS one, 2015 - journals.plos.org
Background Mobile populations present unique challenges to malaria control and
elimination efforts. Each year, a large number of individuals travel to northwest Amhara …