Endogenous microRNA sponges: evidence and controversy
DW Thomson, ME Dinger - Nature Reviews Genetics, 2016 - nature.com
The competitive endogenous RNA (ceRNA) hypothesis proposes that transcripts with
shared microRNA (miRNA) binding sites compete for post-transcriptional control. This …
shared microRNA (miRNA) binding sites compete for post-transcriptional control. This …
Prediction of miRNA targets
A Oulas, N Karathanasis, A Louloupi… - RNA …, 2015 - Springer
Computational methods for miRNA target prediction are currently undergoing extensive
review and evaluation. There is still a great need for improvement of these tools and …
review and evaluation. There is still a great need for improvement of these tools and …
DNMT3A epigenetically regulates key microRNAs involved in epithelial-to-mesenchymal transition in prostate cancer
M Mancini, M Grasso, L Muccillo, F Babbio… - …, 2021 - academic.oup.com
Epithelial-to-mesenchymal transition (EMT) is involved in prostate cancer (PCa) metastatic
progression, and its plasticity suggests epigenetic implications. Deregulation of DNA …
progression, and its plasticity suggests epigenetic implications. Deregulation of DNA …
[HTML][HTML] β-Cell pre-mir-21 induces dysfunction and loss of cellular identity by targeting transforming growth factor beta 2 (Tgfb2) and Smad family member 2 (Smad2) …
S Ibrahim, M Johnson, CH Stephens, J Xu, R Moore… - Molecular …, 2021 - Elsevier
Abstract Objective β-cell microRNA-21 (miR-21) is increased by islet inflammatory stress but
it decreases glucose-stimulated insulin secretion (GSIS). Thus, we sought to define the …
it decreases glucose-stimulated insulin secretion (GSIS). Thus, we sought to define the …
Changes in expression of microRNA potentially targeting key regulators of lipid metabolism in primary gilthead sea bream hepatocytes exposed to phthalates or flame …
Highlights•We analyzed the effects of DiDP/TMCP exposure on the expression levels of 3
miRNAs.•DiDP/TMCP exposure led to a decrease in the expression of each …
miRNAs.•DiDP/TMCP exposure led to a decrease in the expression of each …
Small RNA targets: advances in prediction tools and high-throughput profiling
Simple Summary MicroRNAs (miRNAs) are a category of small RNAs (sRNAs) that have
been found to regulate gene expression. Through the mediation of proteins from the …
been found to regulate gene expression. Through the mediation of proteins from the …
MicroRNA target prediction tools for animals: Where we are at and where we are going to-A systematic review
RMMW Feitosa, P Prieto-Oliveira, H Brentani… - … Biology and Chemistry, 2022 - Elsevier
MicroRNAs (miRNAs) are non-coding RNAs containing 19–26 nucleotides, and they directly
regulate the translation of mRNAs by binding to them. MiRNAs participate in various …
regulate the translation of mRNAs by binding to them. MiRNAs participate in various …
Identifying interaction clusters for miRNA and mRNA pairs in TCGA network
Existing methods often fail to recognize the conversions for the biological roles of the pairs of
genes and microRNAs (miRNAs) between the tumor and normal samples. We have …
genes and microRNAs (miRNAs) between the tumor and normal samples. We have …
MiRduplexSVM: a high-performing miRNA-duplex prediction and evaluation methodology
We address the problem of predicting the position of a miRNA duplex on a microRNA
hairpin via the development and application of a novel SVM-based methodology. Our …
hairpin via the development and application of a novel SVM-based methodology. Our …
Circulating microRNA trafficking and regulation: computational principles and practice
J Cui, J Shu - Briefings in bioinformatics, 2020 - academic.oup.com
Rapid advances in genomics discovery tools and a growing realization of microRNA's
implication in intercellular communication have led to a proliferation of studies of circulating …
implication in intercellular communication have led to a proliferation of studies of circulating …