Understanding neutralising antibodies against SARS-CoV-2 and their implications in clinical practice

NYL Pang, ASR Pang, VT Chow, DY Wang - Military Medical Research, 2021 - Springer
SARS-CoV-2 is a newly identified member of the coronavirus family that has caused the
Coronavirus disease 2019 (COVID-19) pandemic. This rapidly evolving and unrelenting …

Broadly-neutralizing antibodies against emerging SARS-CoV-2 variants

LB Shrestha, N Tedla, RA Bull - Frontiers in immunology, 2021 - frontiersin.org
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
have become a major concern in the containment of current pandemic. The variants …

Molecular insights into receptor binding energetics and neutralization of SARS-CoV-2 variants

M Koehler, A Ray, RA Moreira, B Juniku… - Nature …, 2021 - nature.com
Despite an unprecedented global gain in knowledge since the emergence of SARS-CoV-2,
almost all mechanistic knowledge related to the molecular and cellular details of viral …

Passive immunotherapy against SARS-CoV-2: from plasma-based therapy to single potent antibodies in the race to stay ahead of the variants

WR Strohl, Z Ku, Z An, SF Carroll, BA Keyt, LM Strohl - BioDrugs, 2022 - Springer
The COVID-19 pandemic is now approaching 2 years old, with more than 440 million people
infected and nearly six million dead worldwide, making it the most significant pandemic …

Monoclonal antibody therapies in the management of SARS-CoV-2 infection

E Miguez-Rey, D Choi, S Kim, S Yoon… - Expert Opinion on …, 2022 - Taylor & Francis
ABSTRACT Introduction Neutralizing antibodies (NAbs) that target key domains of the spike
protein in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may have …

Monoclonal antibodies against SARS-CoV-2: current scenario and future perspectives

E Quiros-Roldan, S Amadasi, I Zanella, M Degli Antoni… - Pharmaceuticals, 2021 - mdpi.com
Monoclonal antibodies (mAbs) have been known since the 1970s. However, their
therapeutic potential in the medical field has recently emerged, with the advancement of …

[HTML][HTML] Current treatment strategies for COVID‑19

F Han, Y Liu, M Mo, J Chen… - Molecular …, 2021 - spandidos-publications.com
The spread of the novel severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2)
emerged suddenly at the end of 2019 and the disease came to be known as coronavirus …

Mathematical modeling and analysis of the dynamics of RNA viruses in presence of immunity and treatment: A case study of SARS-CoV-2

K Hattaf, MI El Karimi, AA Mohsen, Z Hajhouji… - Vaccines, 2023 - mdpi.com
The emergence of novel RNA viruses like SARS-CoV-2 poses a greater threat to human
health. Thus, the main objective of this article is to develop a new mathematical model with a …

Anti-SARS-CoV-2 immunoglobulin isotypes, and neutralization activity against viral variants, according to BNT162b2-vaccination and infection history

M Tarkowski, W de Jager, M Schiuma… - Frontiers in …, 2021 - frontiersin.org
Purpose To compare SARS-CoV-2 antigen-specific antibody production and plasma
neutralizing capacity against B. 1 wild-type-like strain, and Gamma/P. 1 and Delta/B. 1.617 …

The emergence of SARS-CoV-2 variants threatens to decrease the efficacy of neutralizing antibodies and vaccines

K Murano, Y Guo, H Siomi - Biochemical Society Transactions, 2021 - portlandpress.com
The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
the cause of the coronavirus disease (COVID-19) pandemic. As of August 2021, more than …