Background Behavioural, cognitive, and pharmacological interventions can all be effective
for insomnia. However, because of inadequate resources, medications are more frequently …

Objective To evaluate sodium-glucose cotransporter-2 (SGLT-2) inhibitors and glucagon-
like peptide-1 (GLP-1) receptor agonists in patients with type 2 diabetes at varying …

A key early step in analysing results of studies of effectiveness is identifying the data type for
the outcome measurements. This chapter considers outcome data of five common types …

Background Schizophrenia is a common, severe, and usually chronic disorder. Maintenance
treatment with antipsychotic drugs can prevent relapse but also causes side-effects. We …

Background Schizophrenia is one of the most common, burdensome, and costly psychiatric
disorders in adults worldwide. Antipsychotic drugs are its treatment of choice, but there is …

Background Depressive disorders are common in children and adolescents.
Antidepressants, psychotherapies, and their combination are often used in routine clinical …

Tillage intensity affects soil microbiological activity in many ways, often driven by changes in
soil organic C (SOC) content. The magnitude and direction of those changes, however …

Abstract Mindfulness-Based Cognitive Therapy (MBCT) and Mindfulness-Based Stress
Reduction (MBSR) emphasize the importance of mindfulness practice at home as an …

Importance Several psychotherapy protocols have been evaluated as adjuncts to
pharmacotherapy for patients with bipolar disorder, but little is known about their …

Background Indications for the use of negative pressure wound therapy (NPWT) are broad
and include prophylaxis for surgical site infections (SSIs). Existing evidence for the …