Bottom-up proteomics (2013–2015): keeping up in the era of systems biology

J Mayne, Z Ning, X Zhang, AE Starr, R Chen… - Analytical …, 2016 - ACS Publications
Over 17,000 papers related to proteomics have been published since our 2011− 2013
review. A subset are true gems reporting amazing applications of proteomics to better …

[HTML][HTML] Cell-free synthesis of stable isotope-labeled internal standards for targeted quantitative proteomics

R Narumi, K Masuda, T Tomonaga, J Adachi… - Synthetic and Systems …, 2018 - Elsevier
High-sensitivity mass spectrometry approaches using selected reaction monitoring (SRM) or
multiple reaction monitoring (MRM) methods are powerful tools for targeted quantitative …

Deep coverage proteomics identifies more low-abundance missing proteins in human testis tissue with Q-exactive HF mass spectrometer

W Wei, W Luo, F Wu, X Peng, Y Zhang… - Journal of Proteome …, 2016 - ACS Publications
Since 2012, missing proteins (MPs) investigation has been one of the critical missions of
Chromosome-Centric Human Proteome Project (C-HPP) through various biochemical …

Proteomics-based tools for evaluation of cell-free protein synthesis

GB Hurst, KG Asano, CJ Doktycz, EJ Consoli… - Analytical …, 2017 - ACS Publications
Cell-free protein synthesis (CFPS) has the potential to produce enzymes, therapeutic
agents, and other proteins, while circumventing difficulties associated with in vivo …

Utilizing experimental mouse model to identify effectors of hepatocellular carcinoma induced by HBx antigen

MH Yang, M Chen, HH Mo, WC Tsai, YC Chang… - Cancers, 2020 - mdpi.com
Hepatocellular carcinoma (HCC) is among the ten most commonly diagnosed cancers and
the fourth leading cause of cancer-related death. Patients with hepatitis B virus (HBV) …

Synthetic strategies for plant signalling studies: molecular toolbox and orthogonal platforms

J Braguy, MD Zurbriggen - The Plant Journal, 2016 - Wiley Online Library
Plants deploy a wide array of signalling networks integrating environmental cues with
growth, defence and developmental responses. The high level of complexity, redundancy …

Progress and pitfalls in finding the 'missing proteins' from the human proteome map

V Segura, A Garin-Muga, E Guruceaga… - Expert Review of …, 2017 - Taylor & Francis
ABSTRACT Introduction: The Human Proteome Project was launched with two main goals:
the comprehensive and systematic definition of the human proteome map and the …

Detection of human p53 in-vitro expressed in a transcription-translation cell-free system by a novel conjugate based on cadmium sulphide nanoparticles

V Barba-Vicente, MJA Parra, JF Boyero-Benito… - Nanomaterials, 2020 - mdpi.com
Here, cadmium sulphide quantum dots (CdS QDs) have been synthetized and
functionalized with Bovine Serum Albumin (BSA) in a colloidal aqueous solution with a …

Clinical implications of recent advances in proteogenomics

M Locard-Paulet, O Pible… - Expert review of …, 2016 - Taylor & Francis
Proteogenomics, the alliance of proteomics, transcriptomics, genomics and bioinformatics,
was first proposed for refining genome annotation using experimental data acquired on …

Utilizing an animal model to identify brain neurodegeneration-related biomarkers in aging

MH Yang, YMA Chen, SC Tu, PL Chi… - International Journal of …, 2021 - mdpi.com
Glycine N-methyltransferase (GNMT) regulates S-adenosylmethionine (SAMe), a methyl
donor in methylation. Over-expressed SAMe may cause neurogenic capacity reduction and …