Background The benefit of complete revascularization in older patients (≥ 75 years of age)
with myocardial infarction and multivessel disease remains unclear. Methods In this …

Intracellular calcium signaling is a universal language source shared by the most part of
biological entities inside cells that, all together, give rise to physiological and functional …

Older patients are underrepresented in prospective studies and randomized clinical trials of
acute coronary syndromes (ACS). Over the last decade, a few specific trials have been …

New-generation drug-eluting stents (DESs) represent the standard of care for patients
undergoing percutaneous coronary intervention (PCI). Recent iterations in DES technology …

Background The role of quantitative flow ratio (QFR) in the treatment of nonculprit vessels of
patients with myocardial infarction (MI) is a topic of ongoing discussion. Objectives This …

BACKGROUND: The FIRE trial (Functional Assessment in Elderly Myocardial Infarction
Patients With Multivessel Disease) enrolled 1445 older (aged≥ 75 years) patients with …

Background The optimal revascularization strategy for elderly patients with acute coronary
syndrome (ACS) remains uncertain. We evaluated the impact of complete revascularization …

Importance Patients with high bleeding risk (HBR) have a poor prognosis, and it is not
known if they may benefit from complete revascularization after myocardial infarction (MI) …

Whether contrast-associated acute kidney injury (CA-AKI) is only a bystander or a risk factor
for mortality in older patients undergoing percutaneous coronary intervention (PCI) is not …

Aims The revascularization strategy to pursue in older myocardial infarction (MI) patients
with multivessel disease (MVD) is currently unknown. For this reason, while waiting for the …