Curcumin and cancer

A Giordano, G Tommonaro - Nutrients, 2019 - mdpi.com
Curcumin, a polyphenol extracted from Curcuma longa in 1815, has gained attention from
scientists worldwide for its biological activities (eg, antioxidant, anti-inflammatory …

Potential role of curcumin and its nanoformulations to treat various types of cancers

MT Kabir, MH Rahman, R Akter, T Behl, D Kaushik… - Biomolecules, 2021 - mdpi.com
Cancer is a major burden of disease globally. Each year, tens of millions of people are
diagnosed with cancer worldwide, and more than half of the patients eventually die from it …

[HTML][HTML] Curcuma longa (Turmeric): Ethnomedicinal uses, phytochemistry, pharmacological activities and toxicity profiles—A review

EJ Iweala, ME Uche, ED Dike, LR Etumnu… - Pharmacological …, 2023 - Elsevier
Introduction Curcuma longa, popularly known as Turmeric, is a rhizomatous herbaceous
perennial plant used in folk medicine for the treatment, prevention, and management of …

[HTML][HTML] Curcumin-loaded alginate hydrogels for cancer therapy and wound healing applications: A review

A Sood, A Dev, SS Das, HJ Kim, A Kumar… - International journal of …, 2023 - Elsevier
Hydrogels have emerged as a versatile platform for a numerous biomedical application due
to their ability to absorb a huge quantity of biofluids. In order to design hydrogels, natural …

Curcumin-based nanoformulations: A promising adjuvant towards cancer treatment

S Hafez Ghoran, A Calcaterra, M Abbasi, F Taktaz… - Molecules, 2022 - mdpi.com
Throughout the United States, cancer remains the second leading cause of death.
Traditional treatments induce significant medical toxic effects and unpleasant adverse …

Curcumin mediates anticancer effects by modulating multiple cell signaling pathways

AB Kunnumakkara, D Bordoloi, C Harsha… - Clinical …, 2017 - portlandpress.com
Curcumin, a component of a spice native to India, was first isolated in 1815 by Vogel and
Pelletier from the rhizomes of Curcuma longa (turmeric) and, subsequently, the chemical …

Curcumin encapsulation in functional PLGA nanoparticles: A promising strategy for cancer therapies

F da Silva Feltrin, T Agner, C Sayer… - Advances in colloid and …, 2022 - Elsevier
Nanoparticles have emerged as promising drug delivery systems for the treatment of several
diseases. Novel cancer therapies have exploited these particles as alternative adjuvant …

The molecular basis for the pharmacokinetics and pharmacodynamics of curcumin and its metabolites in relation to cancer

M Heger, RF van Golen, M Broekgaarden… - Pharmacological …, 2014 - Elsevier
This review addresses the oncopharmacological properties of curcumin at the molecular
level. First, the interactions between curcumin and its molecular targets are addressed on …

Receptor tyrosine kinases and their signaling pathways as therapeutic targets of curcumin in cancer

S Sudhesh Dev, SA Zainal Abidin… - Frontiers in …, 2021 - frontiersin.org
Receptor tyrosine kinases (RTKs) are transmembrane cell-surface proteins that act as signal
transducers. They regulate essential cellular processes like proliferation, apoptosis …

Targeting the EGFR signaling pathway in cancer therapy

P Seshacharyulu, MP Ponnusamy… - Expert opinion on …, 2012 - Taylor & Francis
Introduction: Cancer is a devastating disease; however, several therapeutic advances have
recently been made, wherein EGFR and its family members have emerged as useful …