[HTML][HTML] Anti-carcinogenic glucosinolates in cruciferous vegetables and their antagonistic effects on prevention of cancers

P Soundararajan, JS Kim - Molecules, 2018 - mdpi.com
Glucosinolates (GSL) are naturally occurring β-d-thioglucosides found across the
cruciferous vegetables. Core structure formation and side-chain modifications lead to the …

[HTML][HTML] Therapeutic Potential of Natural Compounds Acting through Epigenetic Mechanisms in Cardiovascular Diseases: Current Findings and Future Directions

P Bontempo, L Capasso, L De Masi, A Nebbioso… - Nutrients, 2024 - mdpi.com
Cardiovascular diseases (CVDs) remain a leading global cause of morbidity and mortality.
These diseases have a multifaceted nature being influenced by a multitude of biochemical …

[HTML][HTML] Beneficial health effects of glucosinolates-derived isothiocyanates on cardiovascular and neurodegenerative diseases

RM Kamal, AF Abdull Razis, NS Mohd Sukri… - Molecules, 2022 - mdpi.com
Neurodegenerative diseases (NDDs) and cardiovascular diseases (CVDs) are illnesses that
affect the nervous system and heart, all of which are vital to the human body. To maintain …

Sulforaphane-role in aging and neurodegeneration

R Santín-Márquez, A Alarcón-Aguilar… - Geroscience, 2019 - Springer
In the last several years, numerous molecules derived from plants and vegetables have
been tested for their antioxidant, anti-inflammatory, and anti-aging properties. One of them is …

Luteolin protects against vascular inflammation in mice and TNF-alpha-induced monocyte adhesion to endothelial cells via suppressing IΚBα/NF-κB signaling …

Z Jia, P Nallasamy, D Liu, H Shah, JZ Li… - The Journal of nutritional …, 2015 - Elsevier
Vascular inflammation plays a significant role in the pathogenesis of atherosclerosis.
Luteolin, a naturally occurring flavonoid present in many medicinal plants and some …

[HTML][HTML] Sulforaphane attenuates muscle inflammation in dystrophin-deficient mdx mice via NF-E2-related factor 2 (Nrf2)-mediated inhibition of NF-κB signaling …

CC Sun, SJ Li, CL Yang, RL Xue, YY Xi, L Wang… - Journal of Biological …, 2015 - ASBMB
Inflammation is widely distributed in patients with Duchenne muscular dystrophy and
ultimately leads to progressive deterioration of muscle function with chronic muscle damage …

[HTML][HTML] Sulforaphane: A nutraceutical against diabetes-related complications

SXH Mthembu, SE Mazibuko-Mbeje… - Pharmacological …, 2023 - Elsevier
There is an increasing interest in the use of nutraceuticals and plant-derived bioactive
compounds from foods for their potential health benefits. For example, as a major active …

A current look at nutraceuticals–Key concepts and future prospects

JP Da Costa - Trends in Food Science & Technology, 2017 - Elsevier
Background Nutraceuticals exist in a legal limbo and the existing legislative efforts remain
confusing, complex and not harmonized throughout the many regions of the Globe. These …

Organic isothiocyanates as hydrogen sulfide donors

A Martelli, V Citi, L Testai, S Brogi… - Antioxidants & Redox …, 2020 - liebertpub.com
Significance: Hydrogen sulfide (H2S), the “new entry” in the series of endogenous
gasotransmitters, plays a fundamental role in regulating the biological functions of various …

[HTML][HTML] Sulforaphane exerts anti-inflammatory effects against lipopolysaccharide-induced acute lung injury in mice through the Nrf2/ARE pathway

T Qi, FEI Xu, X Yan, S Li, H Li - … Journal of Molecular …, 2016 - spandidos-publications.com
Abstract Sulforaphane (1-isothiocyanate-4-methyl sulfonyl butane) is a plant extract
(obtained from cruciferous vegetables, such as broccoli and cabbage) and is known to exert …