Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
Abstract 'Reactive oxygen species'(ROS) is an umbrella term for an array of derivatives of
molecular oxygen that occur as a normal attribute of aerobic life. Elevated formation of the …
molecular oxygen that occur as a normal attribute of aerobic life. Elevated formation of the …
Recent progress in copper nanocluster-based fluorescent probing: a review
Copper nanoclusters (CuNCs) are an attractive alternative to other metal nanoclusters. The
synthesis of CuNCs is highly efficient and fast, with low-cost and without any complicated …
synthesis of CuNCs is highly efficient and fast, with low-cost and without any complicated …
Spatial and temporal control of mitochondrial H2O2 release in intact human cells
MN Hoehne, LJHC Jacobs, KJ Lapacz… - The EMBO …, 2022 - embopress.org
Abstract Hydrogen peroxide (H2O2) has key signaling roles at physiological levels, while
causing molecular damage at elevated concentrations. H2O2 production by mitochondria is …
causing molecular damage at elevated concentrations. H2O2 production by mitochondria is …
Mitophagy initiates retrograde mitochondrial-nuclear signaling to guide retinal pigment cell heterogeneity
S Datta, M Cano, G Satyanarayana, T Liu, L Wang… - Autophagy, 2023 - Taylor & Francis
Age-related macular degeneration (AMD), the leading cause of blindness among the
elderly, is without treatment for early disease. Degenerative retinal pigment epithelial (RPE) …
elderly, is without treatment for early disease. Degenerative retinal pigment epithelial (RPE) …
Real-time monitoring of subcellular H2O2 distribution in Chlamydomonas reinhardtii
J Niemeyer, D Scheuring, J Oestreicher… - The Plant …, 2021 - academic.oup.com
Abstract Hydrogen peroxide (H2O2) is recognized as an important signaling molecule in
plants. We sought to establish a genetically encoded, fluorescent H2O2 sensor that allows …
plants. We sought to establish a genetically encoded, fluorescent H2O2 sensor that allows …
Physiologic implications of reactive oxygen species production by mitochondrial complex I reverse electron transport
JO Onukwufor, BJ Berry, AP Wojtovich - Antioxidants, 2019 - mdpi.com
Mitochondrial reactive oxygen species (ROS) can be either detrimental or beneficial
depending on the amount, duration, and location of their production. Mitochondrial complex I …
depending on the amount, duration, and location of their production. Mitochondrial complex I …
Nrf2 deficiency decreases NADPH from impaired IDH shuttle and pentose phosphate pathway in retinal pigmented epithelial cells to magnify oxidative stress‐induced …
M Cano, S Datta, L Wang, T Liu, M Flores‐Bellver… - Aging …, 2021 - Wiley Online Library
The nuclear factor‐erythroid 2‐related factor‐2 (Nrf2), a major antioxidant transcription
factor, is decreased in several age‐related diseases including age‐related macular …
factor, is decreased in several age‐related diseases including age‐related macular …
Nutrient metabolism, subcellular redox state, and oxidative stress in pancreatic islets and β-cells
Insulin-secreting pancreatic β-cells play a critical role in blood glucose homeostasis and the
development of type 2 diabetes (T2D) in the context of insulin resistance. Based on data …
development of type 2 diabetes (T2D) in the context of insulin resistance. Based on data …
Hyperoxidation of mitochondrial peroxiredoxin limits H2O2‐induced cell death in yeast
G Calabrese, E Peker, PS Amponsah… - The EMBO …, 2019 - embopress.org
Abstract Hydrogen peroxide (H2O2) plays important roles in cellular signaling, yet
nonetheless is toxic at higher concentrations. Surprisingly, the mechanism (s) of cellular …
nonetheless is toxic at higher concentrations. Surprisingly, the mechanism (s) of cellular …
[HTML][HTML] An update on methods and approaches for interrogating mitochondrial reactive oxygen species production
RJ Mailloux - Redox biology, 2021 - Elsevier
The chief ROS formed by mitochondria are superoxide (O 2·−) and hydrogen peroxide (H 2
O 2). Superoxide is converted rapidly into H 2 O 2 and therefore the latter is the chief ROS …
O 2). Superoxide is converted rapidly into H 2 O 2 and therefore the latter is the chief ROS …