Cancer stem cells targets and combined therapies to prevent cancer recurrence
Cancer stem cells (CSCs) control the dynamics of tumorigenesis by self-renewal ability and
differentiation potential. These properties contribute towards tumor malignancy, metastasis …
differentiation potential. These properties contribute towards tumor malignancy, metastasis …
[HTML][HTML] Current updates and research on plant-based vaccines for coronavirus disease 2019
The primary outbreak of severe acute respiratory syndrome coronavirus 2, causing
pneumonia-like symptoms in patients named coronavirus disease 2019 (COVID-19) had …
pneumonia-like symptoms in patients named coronavirus disease 2019 (COVID-19) had …
[HTML][HTML] Intra Q-body: an antibody-based fluorogenic probe for intracellular proteins that allows live cell imaging and sorting
Although intracellular biomarkers can be imaged with fluorescent dye (s)-labeled antibodies,
the use of such probes for precise imaging of intracellular biomarkers in living cells remains …
the use of such probes for precise imaging of intracellular biomarkers in living cells remains …
An in-depth in silico and immunoinformatics approach for designing a potential multi-epitope construct for the effective development of vaccine to combat against …
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the latest of the several
viral pathogens that have acted as a threat to human health around the world. Thus, to …
viral pathogens that have acted as a threat to human health around the world. Thus, to …
[HTML][HTML] In silico and in vitro study of bioactive compounds of Nigella sativa for targeting neuropilins in breast cancer
I Zafar, A Safder, H Imran Afridi, S Riaz… - Frontiers in …, 2023 - frontiersin.org
Introduction: Breast cancer poses a significant global challenge, prompting researchers to
explore novel approaches for potential treatments. Material and Methods: For in vitro study …
explore novel approaches for potential treatments. Material and Methods: For in vitro study …
In silico design of fusion keratinocyte growth factor containing collagen-binding domain for tissue engineering application
Z Amidzadeh, E Rismani, MA Shokrgozar… - Journal of Molecular …, 2023 - Elsevier
Keratinocyte growth factor (KGF) is a potential therapeutic factor in wound healing. However,
its applications have been restricted due to its low stability, short half-life, and limited target …
its applications have been restricted due to its low stability, short half-life, and limited target …
Designing a novel multiepitope peptide vaccine against melanoma using immunoinformatics approach
Z Yazdani, A Rafiei, H Irannejad… - Journal of …, 2022 - Taylor & Francis
Malignant melanoma is the most aggressive and life-threaten skin cancer. Nowadays, the
prevention and treatment of melanoma are challenging areas for researchers and …
prevention and treatment of melanoma are challenging areas for researchers and …
[HTML][HTML] Integrated in silico and experimental approach towards the design of a novel recombinant protein containing an anti-HER2 scFv
Biological therapies, such as recombinant proteins, are nowadays amongst the most
promising approaches towards precision medicine. One of the most innovative …
promising approaches towards precision medicine. One of the most innovative …
In silico analysis of a novel protein in CAR T-cell therapy for the treatment of hematologic cancer through molecular modelling, docking, and dynamics approach
R Mohanty, M Manoswini, AK Dhal… - Computers in Biology and …, 2022 - Elsevier
Cellular therapy has emerged as a key tool in the treatment of hematological malignancies.
An advanced cell therapy known as chimeric antigen receptor T cell therapy (CAR T-cell …
An advanced cell therapy known as chimeric antigen receptor T cell therapy (CAR T-cell …
[HTML][HTML] Designing a polyvalent vaccine targeting multiple strains of varicella zoster virus using integrated bioinformatics approaches
The Varicella Zoster Virus (VZV) presents a global health challenge due to its dual
manifestations of chickenpox and shingles. Despite vaccination efforts, incomplete …
manifestations of chickenpox and shingles. Despite vaccination efforts, incomplete …