Revealing neuronal function through microelectrode array recordings
Microelectrode arrays and microprobes have been widely utilized to measure neuronal
activity, both in vitro and in vivo. The key advantage is the capability to record and stimulate …
activity, both in vitro and in vivo. The key advantage is the capability to record and stimulate …
Multi-electrode array technologies for neuroscience and cardiology
ME Spira, A Hai - Nature nanotechnology, 2013 - nature.com
At present, the prime methodology for studying neuronal circuit-connectivity, physiology and
pathology under in vitro or in vivo conditions is by using substrate-integrated microelectrode …
pathology under in vitro or in vivo conditions is by using substrate-integrated microelectrode …
Transparent, conformable, active multielectrode array using organic electrochemical transistors
W Lee, D Kim, N Matsuhisa… - Proceedings of the …, 2017 - National Acad Sciences
Mechanically flexible active multielectrode arrays (MEA) have been developed for local
signal amplification and high spatial resolution. However, their opaqueness limited optical …
signal amplification and high spatial resolution. However, their opaqueness limited optical …
Neurotechnologies for human cognitive augmentation: current state of the art and future prospects
Recent advances in neuroscience have paved the way to innovative applications that
cognitively augment and enhance humans in a variety of contexts. This paper aims at …
cognitively augment and enhance humans in a variety of contexts. This paper aims at …
NT3-chitosan elicits robust endogenous neurogenesis to enable functional recovery after spinal cord injury
Z Yang, A Zhang, H Duan, S Zhang… - Proceedings of the …, 2015 - National Acad Sciences
Neural stem cells (NSCs) in the adult mammalian central nervous system (CNS) hold the
key to neural regeneration through proper activation, differentiation, and maturation, to …
key to neural regeneration through proper activation, differentiation, and maturation, to …
Materials chemistry of neural interface technologies and recent advances in three-dimensional systems
Advances in materials chemistry and engineering serve as the basis for multifunctional
neural interfaces that span length scales from individual neurons to neural networks, neural …
neural interfaces that span length scales from individual neurons to neural networks, neural …
High-throughput electrophysiology: an emerging paradigm for ion-channel screening and physiology
J Dunlop, M Bowlby, R Peri, D Vasilyev… - Nature reviews Drug …, 2008 - nature.com
Ion channels represent highly attractive targets for drug discovery and are implicated in a
diverse range of disorders, in particular in the central nervous and cardiovascular systems …
diverse range of disorders, in particular in the central nervous and cardiovascular systems …
Integration of cell culture and microfabrication technology
TH Park, ML Shuler - Biotechnology progress, 2003 - Wiley Online Library
Recent progress in cell culture and microfabrication technologies has contributed to the
development of cell‐based biosensors for the functional characterization and detection of …
development of cell‐based biosensors for the functional characterization and detection of …
Deficiency in LRP6-mediated Wnt signaling contributes to synaptic abnormalities and amyloid pathology in Alzheimer's disease
CC Liu, CW Tsai, F Deak, J Rogers, M Penuliar… - Neuron, 2014 - cell.com
Alzheimer's disease (AD) is an age-related neurological disorder characterized by synaptic
loss and dementia. The low-density lipoprotein receptor-related protein 6 (LRP6) is an …
loss and dementia. The low-density lipoprotein receptor-related protein 6 (LRP6) is an …
A three-dimensional multi-electrode array for multi-site stimulation and recording in acute brain slices
MO Heuschkel, M Fejtl, M Raggenbass… - Journal of neuroscience …, 2002 - Elsevier
Several multi-electrode array devices integrating planar metal electrodes were designed in
the past 30 years for extracellular stimulation and recording from cultured neuronal cells and …
the past 30 years for extracellular stimulation and recording from cultured neuronal cells and …