Increased interest in the underlying pathogenesis of primary lateral sclerosis (PLS) and its
relationship to amyotrophic lateral sclerosis (ALS) has corresponded to a growing number of …

Background: With the advances in neuroimaging in amyotrophic lateral sclerosis (ALS), it
has been speculated that multiparametric magnetic resonance imaging (MRI) is capable to …

Objective To investigate structural and functional neural organization in amyotrophic lateral
sclerosis (ALS), primary lateral sclerosis (PLS), and progressive muscular atrophy (PMA) …

Background and purpose Primary lateral sclerosis (PLS) is a progressive upper motor
neuron disorder associated with considerable clinical disability. Symptoms are typically …

Primary lateral sclerosis (PLS) is classically considered a 'pure'upper motor neuron disorder.
Motor cortex atrophy and pyramidal tract degeneration are thought to be pathognomonic of …

Utilizing neuroimaging and machine learning (ML) to differentiate schizophrenia (SZ)
patients from normal controls (NCs) and for detecting abnormal brain regions in …

MRI and PET studies in ALS have consistently shown patterns of functional and structural
changes considered to be the pathological signature of the disease. The constant advance …

While C9orf72-specific imaging signatures have been proposed by both ALS and FTD
research groups and considerable presymptomatic alterations have also been confirmed in …

Introduction: In the last decade, multiparametric magnetic resonance imaging (MRI) has
achieved tremendous advances in applications to amyotrophic lateral sclerosis (ALS) to …

Introduction. Despite the rapid development of neuroimaging techniques, the diagnosis of
amyotrophic lateral sclerosis (ALS) remains a significant challenge. Magnetic resonance …