Uncovering the Hidden Credentials of Brucella Virulence

RM Roop, IS Barton, D Hopersberger… - … and Molecular Biology …, 2021 - Am Soc Microbiol
Bacteria in the genus Brucella are important human and veterinary pathogens. The abortion
and infertility they cause in food animals produce economic hardships in areas where the …

[HTML][HTML] AHL-mediated quorum sensing to regulate bacterial substance and energy metabolism: A review

L Liu, X Zeng, J Zheng, Y Zou, S Qiu, Y Dai - Microbiological Research, 2022 - Elsevier
Substance and energy metabolism are the basis for all life activities and are largely
regulated by cell-to-cell communication. Microbial cell-to-cell communication often occurs by …

Bacterial quorum sensing and phenotypic heterogeneity: how the collective shapes the individual

B Striednig, H Hilbi - Trends in Microbiology, 2022 - cell.com
Bacteria communicate with each other through a plethora of small, diffusible organic
molecules called autoinducers. This cell-density-dependent regulatory principle is termed …

An evolutionary strategy for a stealthy intracellular Brucella pathogen

A Martirosyan, E Moreno, JP Gorvel - Immunological reviews, 2011 - Wiley Online Library
Brucella is an intracellular bacterial pathogen that causes abortion and infertility in mammals
and leads to a debilitating febrile illness that can progress into a long lasting disease with …

Internal affairs: investigating the Brucella intracellular lifestyle

K von Bargen, JP Gorvel… - FEMS microbiology …, 2012 - academic.oup.com
Bacteria of the genus Brucella are Gram-negative pathogens of several animal species that
cause a zoonotic disease in humans known as brucellosis or Malta fever. Within their hosts …

Survival of the fittest: how Brucella strains adapt to their intracellular niche in the host

RM Roop, JM Gaines, ES Anderson… - Medical microbiology …, 2009 - Springer
Brucella strains produce abortion and infertility in their natural hosts and a zoonotic disease
in humans known as undulant fever. These bacteria do not produce classical virulence …

Brucella Modulates Secretory Trafficking via Multiple Type IV Secretion Effector Proteins

S Myeni, R Child, TW Ng, JJ Kupko III, TD Wehrly… - PLoS …, 2013 - journals.plos.org
The intracellular pathogenic bacterium Brucella generates a replicative vacuole (rBCV)
derived from the endoplasmic reticulum via subversion of the host cell secretory pathway …

LuxR-family 'solos': bachelor sensors/regulators of signalling molecules

S Subramoni, V Venturi - Microbiology, 2009 - microbiologyresearch.org
N-Acylhomoserine lactone (AHL) quorum-sensing (QS) signalling is the best-understood
chemical language in proteobacteria. In the last 15 years a large amount of research in …

Identification of VceA and VceC, two members of the VjbR regulon that are translocated into macrophages by the Brucella type IV secretion system

MF De Jong, YH Sun, AB Den Hartigh… - Molecular …, 2008 - Wiley Online Library
Survival and replication inside host cells by Brucella spp. requires a type IV secretion system
(T4SS), encoded by the virB locus. However, the identity of the molecules secreted by the …

Comparative review of brucellosis in small domestic ruminants

CA Rossetti, E Maurizio, UA Rossi - Frontiers in veterinary science, 2022 - frontiersin.org
Brucella melitensis and Brucella ovis are the primary etiological agents of brucellosis in
small domestic ruminants. B. melitensis was first isolated in 1887 by David Bruce in Malta …