SARS-CoV-2 mRNA vaccines: immunological mechanism and beyond

E Bettini, M Locci - Vaccines, 2021 - mdpi.com
To successfully protect against pathogen infection, a vaccine must elicit efficient adaptive
immunity, including B and T cell responses. While B cell responses are key, as they can …

Effect of probiotics and prebiotics on immune response to influenza vaccination in adults: a systematic review and meta-analysis of randomized controlled trials

WT Lei, PC Shih, SJ Liu, CY Lin, TL Yeh - Nutrients, 2017 - mdpi.com
We conducted a meta-analysis to evaluate the effects of probiotics and prebiotics on the
immune response to influenza vaccination in adults. We conducted a literature search of …

The effects of exercise on vaccination responses: a review of chronic and acute exercise interventions in humans

AR Pascoe, MAF Singh, KM Edwards - Brain, Behavior, and Immunity, 2014 - Elsevier
Vaccination programs, although feted for success in reducing infectious disease morbidity
and mortality, are limited by vaccine efficacy, which is particularly problematic in populations …

The inverted CD4/CD8 ratio and associated parameters in 66-year-old individuals: the Swedish HEXA immune study

J Strindhall, M Skog, J Ernerudh, M Bengner, S Löfgren… - Age, 2013 - Springer
Abstract The Swedish OCTO and NONA immune longitudinal studies were able to identify
and confirm an immune risk profile (IRP) predictive of an increased 2-year mortality in very …

Effectiveness of influenza vaccine in aging and older adults: comprehensive analysis of the evidence

PO Lang, A Mendes, J Socquet, N Assir… - … interventions in aging, 2012 - Taylor & Francis
Foremost amongst the diseases preventable by vaccination is influenza. Worldwide,
influenza virus infection is associated with serious adverse events leading to hospitalization …

Zinc, aging, and immunosenescence: an overview

AJR Cabrera - Pathobiology of Aging & Age-related Diseases, 2015 - Taylor & Francis
Zinc plays an essential role in many biochemical pathways and participates in several cell
functions, including the immune response. This review describes the role of zinc in human …

The effects of non-viable Lactobacillus on immune function in the elderly: a randomised, double-blind, placebo-controlled study

M Maruyama, R Abe, T Shimono… - … journal of food …, 2016 - Taylor & Francis
Forty-two participants in two nursing homes who were≥ 65 years of age were randomised
to receive a jelly containing 10 billion heat-killed Lactobacillus paracasei MCC1849 cells …

Thymic function failure and C-reactive protein levels are independent predictors of all-cause mortality in healthy elderly humans

S Ferrando-Martínez, MC Romero-Sánchez, R Solana… - Age, 2013 - Springer
Relationship between thymic function and elderly survival has been suspected, despite the
fact that formal proof is elusive due to technical limitations of thymic function-related markers …

High non-responsiveness of males and the elderly to standard hepatitis B vaccination among a large cohort of healthy employees

APA Vermeiren, CJPA Hoebe… - Journal of Clinical …, 2013 - Elsevier
Background Hepatitis B virus infection is a major health problem. Although non-response is
known to increase with age, hepatitis B vaccinations are considered to have only minor non …

How can we improve the vaccination response in older people? Part II: targeting immunosenescence of adaptive immunity cells

M Garnica, A Aiello, ME Ligotti, G Accardi… - International Journal of …, 2022 - mdpi.com
The number of people that are 65 years old or older has been increasing due to the
improvement in medicine and public health. However, this trend is not accompanied by an …