[HTML][HTML] Roles of Hsp90 in Candida albicans morphogenesis and virulence

N Robbins, LE Cowen - Current Opinion in Microbiology, 2023 - Elsevier
Highlights•Hsp90 is a molecular chaperone that modulates the function of many client
proteins.•Morphogenesis is an important Candida albicans virulence trait.•Hsp90 regulates …

Transcriptional control of hyphal morphogenesis in Candida albicans

S Villa, M Hamideh, A Weinstock, MN Qasim… - FEMS yeast …, 2020 - academic.oup.com
Candida albicans is a multimorphic commensal organism and opportunistic fungal pathogen
in humans. A morphological switch between unicellular budding yeast and multicellular …

Candida albicans selection for human commensalism results in substantial within-host diversity without decreasing fitness for invasive disease

FM Anderson, ND Visser, KR Amses… - Plos …, 2023 - journals.plos.org
Candida albicans is a frequent colonizer of human mucosal surfaces as well as an
opportunistic pathogen. C. albicans is remarkably versatile in its ability to colonize diverse …

A Candida auris–specific adhesin, Scf1, governs surface association, colonization, and virulence

DJ Santana, JAE Anku, G Zhao, R Zarnowski… - Science, 2023 - science.org
Candida auris is an emerging fungal pathogen responsible for health care–associated
outbreaks that arise from persistent surface and skin colonization. We characterized the …

Evolutionary and reverse engineering to increase Saccharomyces cerevisiae tolerance to acetic acid, acidic pH, and high temperature

PC Salas-Navarrete, AIM de Oca Miranda… - Applied Microbiology …, 2022 - Springer
Saccharomyces cerevisiae scarcely grows on minimal media with acetic acid, acidic pH, and
high temperatures. In this study, the adaptive laboratory evolution (ALE), whole-genome …

Forward and reverse genetic dissection of morphogenesis identifies filament-competent Candida auris strains

DJ Santana, TR O'Meara - Nature communications, 2021 - nature.com
Candida auris is an emerging healthcare-associated pathogen of global concern. Recent
reports have identified C. auris isolates that grow in cellular aggregates or filaments, often …

Regulatory mechanisms controlling morphology and pathogenesis in Candida albicans

D Kadosh - Current opinion in microbiology, 2019 - Elsevier
Highlights•There is a strong association between C. albicans morphology and virulence.•C.
albicans morphology control mechanisms may serve as important antifungal …

[PDF][PDF] Identification of triazenyl indoles as inhibitors of fungal fatty acid biosynthesis with broad-spectrum activity

KR Iyer, SC Li, NM Revie, JW Lou, D Duncan… - Cell Chemical …, 2023 - cell.com
Rising drug resistance among pathogenic fungi, paired with a limited antifungal arsenal,
poses an increasing threat to human health. To identify antifungal compounds, we screened …

Factors affecting yeast ethanol tolerance and fermentation efficiency

SS Vamvakas, J Kapolos - World Journal of Microbiology and …, 2020 - Springer
Alcohol fermentation is a key process in wine, beer, alcoholic beverage production,
bioethanol production by means of carbohydrate sources, and food industry byproducts …

Heat Shock Transcription Factor CgHSF1 Is Required for Melanin Biosynthesis, Appressorium Formation, and Pathogenicity in Colletotrichum gloeosporioides

X Gao, Q Wang, Q Feng, B Zhang, C He, H Luo, B An - Journal of Fungi, 2022 - mdpi.com
Heat shock transcription factors (HSFs) are a family of transcription regulators. Although
HSFs' functions in controlling the transcription of the molecular chaperone heat shock …