Stroke disrupts the homeostatic balance within the brain and is associated with a significant
accumulation of necrotic cellular debris, fluid, and peripheral immune cells in the central …

Despite recent therapeutic advances, ischemic stroke is still a leading cause of death and
disability. There is renewed attention on peripheral inflammatory signaling as a way of …

Background To identify the patients at greatest odds for systemic inflammatory response
syndrome (SIRS) and examine the association between SIRS and outcomes in patients …

Stroke induces a local inflammatory reaction and a plethora of innate immune responses in
the brain where antigen-presenting cells become prominent. However, to date, it is still …

Systolic dysfunction was recently described following traumatic brain injury (TBI), and
systemic inflammation may be a contributing mechanism. Our aims were to 1) examine the …

Elucidating action mechanisms of Chinese medicines has remained a challenging task due
to the chemical and biological complexity that needs to be resolved. In this study we applied …

Objective: Systemic inflammatory response syndrome (SIRS) may be related to poor
outcomes after intracerebral hemorrhage (ICH). Methods: The Ethnic/Racial Variations of …

Animal models have demonstrated the deleterious contribution of splenic immunocytes on
secondary brain injury after stroke. While previous work has demonstrated splenic …

Objective The aim of the study was to compare the prevalence, type, and severity of sleep
apnea during the acute phase of ischemic stroke among patients either receiving or not …

Stroke is a devastating disease with high morbidity, disability, and mortality, among which
ischemic stroke is more common. However, there is still a lack of effective methods to …