The papillomavirus E2 proteins are pivotal to the viral life cycle and have well characterized
functions in transcriptional regulation, initiation of DNA replication and partitioning the viral …

Human papillomaviruses (HPV) are small DNA viruses that contain a compact and non-
redundant genome. HPV, with the help of only few genes, can achieve a complete …

Enhanced expression of the HPV 16 E6‐E7 oncogenes may trigger neoplastic
transformation of the squamous epithelial cells at the uterine cervix. The HPV E2 protein is a …

Disruption of DNA methylation patterns is one of the hallmarks of cancer. Similar to other
cancer types, human papillomavirus (HPV)-driven head and neck cancer (HNC) also …

ABSTRACT A conserved E8∧ E2 spliced mRNA is detected in keratinocytes transfected
with human papillomavirus type 16 (HPV-16) plasmid DNA. Expression of HPV-16 E8∧ E2 …

Human Papillomaviruses (HPV) cause widespread infections in humans, resulting in latent
infections or diseases ranging from benign hyperplasia to cancers. HPV-induced …

Over 100 genotypes of human papillomaviruses (HPVs) have been identified as being
responsible for unapparent infections or for lesions ranging from benign skin or genital warts …

The intrinsic flexibility of DNA and the difficulty of identifying its interaction surface have long
been challenges that prevented the development of efficient protein–DNA docking methods …

E2 protein binding to the four E2 binding sites (E2BSs) at the long control region of Human
Papillomavirus (HPV) 16/18 genome may exert either transcriptional activation/repression …

Papillomavirus E2 protein is required for the replication and maintenance of viral genomes
and transcriptional regulation of viral genes. E2 functions through sequence-specific binding …