[HTML][HTML] Antidiabetic phytochemicals from medicinal plants: prospective candidates for new drug discovery and development

S Alam, MMR Sarker, TN Sultana… - Frontiers in …, 2022 - frontiersin.org
Diabetes, a chronic physiological dysfunction affecting people of different age groups and
severely impairs the harmony of peoples' normal life worldwide. Despite the availability of …

[HTML][HTML] The role of natural antioxidants in cisplatin-induced hepatotoxicity

N Abd Rashid, SAS Abd Halim, SL Teoh… - Biomedicine & …, 2021 - Elsevier
Cisplatin is a potent platinum-based anticancer drug approved by the Food Drug
Administration (FDA) in 1978. Despite its advantages against solid tumors, cisplatin confers …

[HTML][HTML] Phytochemistry, biological activities and potential of annatto in natural colorant production for industrial applications–A review

LJ Rather, F Mohammad - Journal of advanced research, 2016 - Elsevier
Bixa orellana commonly known as annatto is one of the oldest known natural dye yielding
plants native to Central and South America. Various parts of annatto have been widely used …

[HTML][HTML] Carotenoid Derivates in Achiote (Bixa orellana) Seeds: Synthesis and Health Promoting Properties

R Rivera-Madrid, M Aguilar-Espinosa… - Frontiers in plant …, 2016 - frontiersin.org
Bixa orellana (family Bixaceae) is a neotropical fast growing perennial tree of great agro-
industrial value because its seeds have a high carotenoid content, mainly bixin. It has been …

The role of bixin as antioxidant, anti-inflammatory, anticancer, and skin protecting natural product extracted from Bixa orellana L

A Ashraf, MU Ijaz, S Muzammil, MM Nazir, S Zafar… - Fitoterapia, 2023 - Elsevier
Since long, medicinal plants or herbs are being used in different traditional treatment
systems as therapeutic agents to treat a variety of illnesses. Bixa orellana L., an medicinal …

Edible fruits from Brazilian biodiversity: A review on their sensorial characteristics versus bioactivity as tool to select research

N Teixeira, JCS Melo, LF Batista, J Paula-Souza… - Food research …, 2019 - Elsevier
The Brazilian flora is very rich in edible fruits but only a fraction of this potential is known and
properly used. In this study, we discuss the importance of Brazilian edible fruits using data …

[HTML][HTML] Therapeutic potential of bixin on inflammation: a mini review

S Shadisvaaran, KY Chin, S Mohd-Said… - Frontiers in Nutrition, 2023 - frontiersin.org
Chronic inflammation is the underlying mechanism for many diseases. Thus, inflammatory
signaling pathways are valuable targets for new treatment modalities. Natural products have …

Bixin, an apocarotenoid isolated from Bixa orellana L., sensitizes human melanoma cells to dacarbazine-induced apoptosis through ROS-mediated cytotoxicity

RG de Oliveira Júnior, A Bonnet, E Braconnier… - Food and chemical …, 2019 - Elsevier
Cutaneous melanoma has a high capacity to metastasize and significant resistance to
conventional therapeutic protocols, which makes its treatment difficult. The combination of …

[PDF][PDF] Synthesis, biological activity, and in silico study of bioesters derived from bixin by the CALB enzyme

AM da Fonseca, ÍB de Freitas… - … Res. Appl. Chem, 2022 - biointerfaceresearch.com
Biocatalysis is a branch of biotechnology that aims at the chemical transformation of a
compound by using enzymes of known specificity. There are already several studies that …

Nephroprotective plant species used in traditional Mayan Medicine for renal-associated diseases

R Castañeda, A Cáceres, SM Cruz, JA Aceituno… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance The prevalence of kidney disease has increased rapidly in
recent years and has emerged as one of the leading causes of mortality worldwide. Natural …