Atherosclerosis is the main risk factor for cardiovascular disease (CVD), which is the leading
cause of mortality worldwide. Atherosclerosis is initiated by endothelium activation and …

Major reactive oxygen species (ROS)–producing systems in vascular wall include NADPH
(reduced form of nicotinamide adenine dinucleotide phosphate) oxidase, xanthine oxidase …

An ideal animal model of atherosclerosis resembles human anatomy and pathophysiology
and has the potential to be used in medical and pharmaceutical research to obtain results …

Atherosclerosis is the disease process that underlies heart attack and stroke. Advanced
lesions at risk of rupture are characterized by the pathological accumulation of diseased …

Atherosclerosis is a maladaptive, nonresolving chronic inflammatory disease that occurs at
sites of blood flow disturbance. The disease usually remains silent until a breakdown of …

Atherosclerosis is a multifocal alteration of the vascular wall of medium and large arteries
characterized by a local accumulation of cholesterol and non-resolving inflammation …

Blood vessels are exposed to multiple mechanical forces that are exerted on the vessel wall
(radial, circumferential and longitudinal forces) or on the endothelial surface (shear stress) …

Atherosclerosis underlies the predominant number of cardiovascular diseases and remains
a leading cause of morbidity and mortality worldwide. The development, progression and …

Atherosclerosis, a chronic cardiovascular disease caused by plaque development in
arteries, remains a leading cause of morbidity and mortality. Atherosclerotic plaques are …

The inflammatory microenvironment involves changes in pH and protein phosphorylation
state and is closely related to the occurrence and development of atherosclerosis (AS) …