The suppressor of cytokine signalling (SOCS) proteins were, as their name suggests, first
described as inhibitors of cytokine signalling. While their actions clearly now extend to other …

Cytokines are key modulators of T cell biology, but their influence can be attenuated by
suppressors of cytokine signaling (SOCS), a family of proteins consisting of eight members …

Cytokine and growth factor signaling mediates essential roles in the differentiation,
proliferation, survival and function of a number of cell lineages. This is achieved via specific …

Respiratory syncytial virus (RSV) is the most common single cause of respiratory
hospitalisation of infants and is the second largest cause of lower respiratory infection …

Hypothalamic insulin signaling is essential to the maintenance of glucose and energy
homeostasis. During pathological states, such as obesity and type 2 diabetes mellitus …

The suppressors of cytokine signalling (SOCS) box is a structural domain found at the C-
terminus of over 70 human proteins. It is usually coupled to a protein interaction module …

In mammals, suppressor of cytokine signalling (CISH, SOCS1 to SOCS7) factors control
signalling pathways involved in the regulation of numerous physiological processes …

First discovered as inhibitors of cytokine signalling, the suppressor of cytokine signalling
(SOCS) proteins have appeared, over recent years, as potent repressors of other signalling …

The distinct lack of cell lines derived from the adult brain is evident. Ciliary neurotrophic
factor (CNTF) triggers neurogenesis in primary culture from adult mouse hypothalamus, as …

Suppressors of cytokine signalling (SOCS) proteins are modulators of cytokine and growth
factor signalling whose aberrant regulation has been linked to a variety of inflammatory and …