The importance of vitamin d metabolism as a potential prophylactic, immunoregulatory and neuroprotective treatment for COVID-19
Y Xu, DJ Baylink, CS Chen, ME Reeves, J Xiao… - Journal of translational …, 2020 - Springer
Abstract The coronavirus disease 2019 (COVID-19) pandemic has led to a declaration of a
Public Health Emergency of International Concern by the World Health Organization. As of …
Public Health Emergency of International Concern by the World Health Organization. As of …
Targeting LSD1 for acute myeloid leukemia (AML) treatment
Targeted therapy for acute myeloid leukemia (AML) is an effective strategy, but currently
there are very limited therapeutic targets for AML treatment. Histone lysine specific …
there are very limited therapeutic targets for AML treatment. Histone lysine specific …
[HTML][HTML] Vitamin D effects on cell differentiation and stemness in cancer
A Fernández-Barral, P Bustamante-Madrid… - Cancers, 2020 - mdpi.com
Vitamin D 3 is the precursor of 1α, 25-dihydroxyvitamin D 3 (1, 25 (OH) 2 D 3), a pleiotropic
hormone that is a major regulator of the human genome. 1, 25 (OH) 2 D 3 modulates the …
hormone that is a major regulator of the human genome. 1, 25 (OH) 2 D 3 modulates the …
Analysis of serum cytokine and protective vitamin D levels in severe cases of COVID‐19
In this study, we investigated the role and relationship between the cytokine profile and
protective vitamin D by measuring their serum levels in COVID‐19 intensive care unit …
protective vitamin D by measuring their serum levels in COVID‐19 intensive care unit …
Vitamin D receptor controls cell stemness in acute myeloid leukemia and in normal bone marrow
E Paubelle, F Zylbersztejn, TT Maciel, C Carvalho… - Cell reports, 2020 - cell.com
Vitamin D (VD) is a known differentiating agent, but the role of VD receptor (VDR) is still
incompletely described in acute myeloid leukemia (AML), whose treatment is based mostly …
incompletely described in acute myeloid leukemia (AML), whose treatment is based mostly …
Vitamin D inhibits the epithelial-mesenchymal transition by a negative feedback regulation of TGF-β activity
C Ricca, A Aillon, M Viano, L Bergandi, E Aldieri… - The Journal of Steroid …, 2019 - Elsevier
Vitamin D and TGF-β exert opposite effects on epithelial-mesenchymal EMT transition. Here
we report a novel mechanism of action of TGF-β that promotes the counteracting activity of …
we report a novel mechanism of action of TGF-β that promotes the counteracting activity of …
[HTML][HTML] Calcitriol inhibits proliferation and potentially induces apoptosis in B16–F10 cells
EK Sutedja, D Amarassaphira… - Medical Science …, 2022 - ncbi.nlm.nih.gov
Background Melanoma is one of the most aggressive types of cancer and it has shown a
remarkable surge in incidence during the last 50 years. Melanoma has been projected to be …
remarkable surge in incidence during the last 50 years. Melanoma has been projected to be …
Vitamin C and D supplementation in acute myeloid leukemia
PL Mouchel, E Bérard, S Tavitian, N Gadaud… - Blood …, 2023 - ashpublications.org
Recent studies have highlighted the role of vitamin C and D in acute myeloid leukemia
(AML). In 2018, we changed our practices to add both vitamins to the supportive care for all …
(AML). In 2018, we changed our practices to add both vitamins to the supportive care for all …
Targeting the Hallmarks of Aging with Vitamin D: Starting to Decode the Myth
C Ruggiero, L Tafaro, L Cianferotti, F Tramontana… - Nutrients, 2024 - mdpi.com
Aging is the result of several complex and multifactorial processes, where several agents
contribute to an increased intrinsic vulnerability and susceptibility to age-related diseases …
contribute to an increased intrinsic vulnerability and susceptibility to age-related diseases …
Dimethyl fumarate and vitamin D derivatives cooperatively enhance VDR and Nrf2 signaling in differentiating AML cells in vitro and inhibit leukemia progression in a …
M Nachliely, A Trachtenberg, B Khalfin… - The Journal of steroid …, 2019 - Elsevier
Acute myeloid leukemia (AML) is one of the deadliest hematological malignancies without
effective treatment for most patients. Vitamin D derivatives (VDDs)-active metabolites 1α, 25 …
effective treatment for most patients. Vitamin D derivatives (VDDs)-active metabolites 1α, 25 …