Vagal sensory neurons constitute the major afferent supply to the airways and lungs.
Subsets of afferents are defined by their embryological origin, molecular profile …

Chronic heart failure (CHF) is a progressive, debilitating disease, resulting in a decline in the
quality of life of the patients and in very high social economic costs. CHF is a complex …

Capsaicin, a selective activator of the chemo-and heat-sensitive transient receptor potential
(TRP) V1 cation channel, has characteristic feature of causing long-term functional and …

In what follows, we have three goals. The first is to explicate pragmatism, which means
looking at it in the context of the history of philosophy, psychology, and science with the …

Cough is an important protective mechanism for clearing the airways but becomes a
troublesome, and often difficult to treat, symptom in respiratory disease. Although cough can …

Vagus nerve stimulation (VNS) treats patients with drug‐resistant epilepsy, depression and
heart failure, but the mechanisms responsible are uncertain. The mild stimulus intensities …

The sympathetic nervous system vitally regulates autonomic functions, including cardiac
activity. Postganglionic neurons of the sympathetic chain ganglia relay signals from the …

Action potentials trigger synaptic terminals to synchronously release vesicles, but some
vesicles release spontaneously. G-protein-coupled receptors (GPCRs) can modulate both of …

Advances in our understanding of brain mechanisms for the hypoxic ventilatory response,
coordinated changes in blood pressure, and the long-term consequences of chronic …

The nucleus of the solitary tract (NTS) receives viscerosensory information from the vagus
nerve to regulate diverse homeostatic reflex functions. The NTS projects to a wide network of …