Exploring the potential of bioactive peptides: From natural sources to therapeutics

K Purohit, N Reddy, A Sunna - International Journal of Molecular …, 2024 - mdpi.com
Bioactive peptides, specific protein fragments with positive health effects, are gaining
traction in drug development for advantages like enhanced penetration, low toxicity, and …

Mastoparans: a group of multifunctional α-helical peptides with promising therapeutic properties

CJC de Santana, OR Pires Júnior, W Fontes… - Frontiers in Molecular …, 2022 - frontiersin.org
Biologically active peptides have been attracting increasing attention, whether to improve
the understanding of their mechanisms of action or in the search for new therapeutic drugs …

Wasp venom biochemical components and their potential in biological applications and nanotechnological interventions

A Abd El-Wahed, N Yosri, HH Sakr, M Du… - Toxins, 2021 - mdpi.com
Wasps, members of the order Hymenoptera, are distributed in different parts of the world,
including Brazil, Thailand, Japan, Korea, and Argentina. The lifestyles of the wasps are …

Therapeutic potential of antimicrobial peptides against pathogenic protozoa

CL Hagemann, AJ Macedo, T Tasca - Parasitology Research, 2024 - Springer
Protozoal infections cause significant morbidity and mortality in humans and animals. The
use of several antiprotozoal drugs is associated with serious adverse effects and resistance …

Activity of Anti-Microbial Peptides (AMPs) against Leishmania and Other Parasites: An Overview

R El-Dirany, H Shahrour, Z Dirany, F Abdel-Sater… - Biomolecules, 2021 - mdpi.com
Anti-microbial peptides (AMPs), small biologically active molecules, produced by different
organisms through their innate immune system, have become a considerable subject of …

Antimicrobial peptides isolated from insects and their potential applications

N Azmiera, A Krasilnikova, S Sahudin, H Al-Talib… - Journal of Asia-Pacific …, 2022 - Elsevier
Antimicrobial peptides (AMPs) in insects have the potential to be developed as
chemotherapy agents against numerous microbial species. This article reviewed the existing …

[HTML][HTML] Latarcins: versatile spider venom peptides

PV Dubovskii, AA Vassilevski, SA Kozlov… - Cellular and Molecular …, 2015 - Springer
Arthropod venoms feature the presence of cytolytic peptides believed to act synergetically
with neurotoxins to paralyze prey or deter aggressors. Many of them are linear, ie, lack …

[HTML][HTML] Profiling hymenopteran venom toxins: Protein families, structural landscape, biological activities, and pharmacological benefits

JC Guido-Patiño, F Plisson - Toxicon: X, 2022 - Elsevier
Hymenopterans are an untapped source of venom secretions. Their recent proteo-
transcriptomic studies have revealed an extraordinary pool of toxins that participate in …

Antifungal activity, toxicity, and membranolytic action of a mastoparan analog peptide

JL Singulani, MC Galeane, MD Ramos… - Frontiers in cellular …, 2019 - frontiersin.org
Invasive fungal infections, such as cryptococcosis and paracoccidioidomycosis are
associated with significant rates of morbidity and mortality. Cryptococcosis, caused by …

Anti-parasitic peptides from arthropods and their application in drug therapy

AF Lacerda, PB Pelegrini, DM de Oliveira… - Frontiers in …, 2016 - frontiersin.org
Africa, Asia, and Latin America are regions highly affected by endemic diseases, such as
Leishmaniasis, Malaria, and Chagas' disease. They are responsible for the death of 1000s …